3 citations
,
November 2020 in “Planta medica international open” Plant-made bFGF helps cells grow and boosts collagen.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
May 2024 in “Archives of Dermatological Research” TAT-GILZ peptide promotes hair growth by boosting stem cell activity.
105 citations
,
December 1998 in “Archives of Dermatological Research” Dermal papilla cells mainly drive blood vessel growth in hair follicles.
May 2022 in “Journal of Immunology” A parasite molecule can speed up skin healing and reduce scarring.
PDGF signaling is crucial for cell development, wound healing, and fluid regulation in the body.
2 citations
,
January 2015 in “BioMed Research International” Growth factor treatments are increasingly used in medicine but require more research to fully understand their mechanisms.
August 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” FGF18 controls hair cycle rest and growth phases.
28 citations
,
August 2005 in “Journal of Investigative Dermatology” TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.
FGF9 helps hair follicles grow in small-tailed Han sheep by affecting cell growth and certain signaling pathways.
5 citations
,
June 2024 in “Developmental Cell” Activating TRPV1 can boost hair growth by involving neurons, macrophages, and fibroblasts.
6 citations
,
October 2023 in “Animal Biotechnology” A specific gene variation in goats is linked to better growth traits.
56 citations
,
June 2002 in “Biomaterials” Controlled release of VEGF in a collagen hydrogel boosts hair growth in mice.
April 2016 in “Journal of Investigative Dermatology” Boosting HGF signaling could improve the creation of hair follicles in lab-made skin.
9 citations
,
December 1996 in “Cell Biology and Toxicology” Hair follicle cells produce VEGF, which can promote blood vessel cell growth and movement.
158 citations
,
February 2012 in “Journal of Investigative Dermatology” FGF18 helps keep hair in its resting phase, affecting hair growth cycles.
1 citations
,
February 2009 in “Journal of Investigative Dermatology” VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.
September 2008 in “Kitasato medical journal”
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
April 2015 in “MOJ Cell Science & Report” Rat hair follicle stem cells can be used to improve blood vessel growth in engineered skin.
1 citations
,
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” GTL1 is needed to control root hair growth and prevent problems when there are too many nutrients.
1 citations
,
April 1998 in “PubMed” April 2026 in “Frontiers in Cell and Developmental Biology” G-protein-coupled receptors (GPCRs) are crucial in the wound healing process, influencing immune cell recruitment and signaling pathways like Hedgehog-GLI, Hippo-YAP1, and Wnt/β-catenin, which are involved in epidermal cell proliferation and differentiation. By modifying GPCR activity with agonists or antagonists, it is possible to impact immune cell infiltration, inflammatory mediator production, and the rate of wound healing. This review discusses the fundamental mechanisms of GPCR signaling in wound healing and recent discoveries about their roles and functions.
1 citations
,
August 2022 in “International Journal of Molecular Sciences” FGF12 is important for hair growth and could be targeted for hair loss treatment.
Lack of Fgf21 slows hair growth by affecting gene interactions.
10 citations
,
February 2019 in “Journal of cellular physiology” TGF-β2 helps yak hair follicles enter the regression phase, while HSP70 tries to prevent it.
February 2023 in “Journal of Plant Physiology” 48 citations
,
May 2002 in “Journal of Anatomy” VEGFs increase blood vessel permeability, especially in diseases like cancer and heart disease.
January 2021 in “Research Square (Research Square)” STAT3 reduces FST gene activity and cell growth, affecting hair development and wool quality.
990 citations
,
October 1999 in “Development” Activated LEF/TCF complexes are crucial for hair development and cycling.