research Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C
Collagen VI and Semaphorin 3C are important for hair pigmentation and could help treat pigmentation disorders.
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research Influence of Immune Cells and Circulating Inflammatory Cytokines on Pathological Scars: A Mendelian Randomization Study
Immune cells and cytokines significantly affect pathological scar development.
research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect
A PIK3CA mutation in Schwann cells causes severe nerve damage and increased glycolysis, but early treatment can help.
research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics
Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
research Mitochondrial deoxyguanosine kinase depletion induced ROS causes melanocyte stem cell exhaustion and hair greying
Lack of a certain enzyme causes hair to grey early by damaging stem cells, but an antioxidant can help prevent this.
research Severe Unilateral Alopecia in a Long-Term Surviving Male Adolescent Glioblastoma Multiforme Patient
There's an urgent need for better treatments for hair loss caused by radiation therapy.
research Fibrosing alopecia in a pattern distribution after hair transplantation: A case report and literature review
Hair transplants can trigger a rare scarring hair loss that is hard to treat.
research Fgf21 Deficiency Delays Hair Follicle Cycling and Modulates miRNA–Target Gene Interactions in Mice
Lack of Fgf21 slows hair growth by affecting gene interactions.
research Th1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata
CD4 T cells need IFN-γ to cause hair loss in alopecia areata.
research Causal Relationship Between Gut Microbiota and Androgenic Alopecia: A Mendelian Randomization Analysis
Certain gut bacteria may protect against or increase the risk of hair loss.
research RNase L represses hair follicle regeneration through altered innate immune signaling
RNase L hinders hair growth by altering immune signals.
research Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis
Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
research Buddha's Way and Modern Approach to Overcome Stress and Anxiety
Buddhist meditation techniques are better for reducing stress and anxiety than modern methods.
research Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells
CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.
research Role of DNA Methylation in the Pathogenesis of Skin Disorders: Mechanisms, Inhibitors of Methylation‐Related Enzyme, and Molecular Docking Studies
Targeting DNA methylation can help treat skin disorders and cancers.
research Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells
CRH causes hair loss by reducing cell survival in hair follicles.
research Manejo das condições pós-COVID: guia e infográficos para orientar profissionais da saúde
A guide and infographics were created to help healthcare professionals manage post-COVID conditions effectively.
research Genetic variants in androgenetic alopecia: insights from scalp RNA sequencing data
Certain genetic variants and pathways are linked to hair loss.
research 651 Epigenetic regulation of macrophage activity by glutamine during wound healing
Glutamine helps macrophages reduce inflammation and improve wound healing.
research LB1034 Meta-analysis of scalp transcriptome defines alopecia areata subtypes and molecular response to four (4) treatments with jak inhibiting properties
JAK inhibitors improve hair growth in alopecia areata, especially in patchy types.
research Editorial: Untangle the broad connections and tight interactions between human microbiota and complex diseases through data-driven approaches, volume II
Data-driven methods can help understand microbiota's role in diseases and develop personalized treatments.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Skin alterations as possible clinical markers of diabetes mellitus and metabolic syndrome
Skin changes can signal diabetes and metabolic issues, aiding early diagnosis and treatment.
research Immune niches for hair follicle development and homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research Trichoscopic findings in children and adults with alopecia areata: A comparative study
Children with alopecia areata have more exclamation mark hairs and fewer yellow dots than adults.
research Understanding Type 3 Innate Lymphoid Cells and Crosstalk with the Microbiota: A Skin Connection
Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.
research Integrated-omics profiling unveils the disparities of host defense to ECM scaffolds during wound healing in aged individuals
Aged individuals heal wounds less effectively due to specific immune cell issues.
research Androgen excess: a hallmark of polycystic ovary syndrome
Excess androgens may cause PCOS, not just be a symptom.
research Joint Public Review: TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling
TLR2 is crucial for hair growth and regeneration, and boosting it can help prevent hair loss.
research ISID0197 - Quantitative analysis of hair loss in mice utilizing imageJ improves the efficacy evaluation of alopecia areata induction in the C3H/HeJ mouse model
A new image-based method improves accuracy in measuring hair loss in mice.