The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.
179 citations
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November 2022 in “Frontiers in Plant Science” WRKY transcription factors help plants manage stress and support growth.
6 citations
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September 2021 in “Experimental Brain Research” Rats have different touch receptors in their paws that help with movement and handling objects.
July 2024 in “Chemical Engineering Journal” A new microneedle system with minoxidil nanoparticles effectively promotes hair regrowth with fewer side effects.
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
January 2022 in “Skin appendage disorders” A woman with alopecia totalis regrew dark hair in bands after using a corticosteroid ointment.
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April 1993 in “PubMed” Human hair cells can change based on their environment, especially interactions with certain skin cells.
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May 2014 in “Biochemical Society Transactions” Environmental cues can change the fate and function of epithelial cells, with potential for cell therapy.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
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August 2014 in “PLoS ONE” GFRα2 is essential for controlling neuron size but not for target innervation in certain sensory neurons.
45 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Understanding hair follicles through various models can help develop new treatments for hair disorders.
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January 2018 in “Science of the total environment” Australian fur seals' fur shows high levels of pollutants, which may be linked to hair loss in young female seals.
3 citations
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January 2023 in “International journal of molecular sciences” Certain miRNAs play a key role in the growth of cashmere by affecting hair follicle development and regeneration.
TNFα and interleukin-1 blockers reduce skin inflammation from EGFR antibody therapy.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” Spiny mice have a unique skin structure that helps them heal and regenerate quickly.
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March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
June 2019 in “Problems of Cryobiology and Cryomedicine”
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June 2021 in “Journal of the European Academy of Dermatology and Venereology” Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.
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November 2023 in “Immunity & ageing” TLR4 is important in aging-related diseases and could be a new treatment target.
48 citations
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July 1988 in “PubMed” Rhino mice show significant meibomian gland changes, making them a potential model for studying gland disorders.
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July 2017 in “Journal of cosmetic dermatology” Infrared thermography, especially with dermoscopy, improves accuracy in diagnosing active hair loss due to inflammation.
10 citations
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March 2024 in “Frontiers in Bioengineering and Biotechnology” Photothermal hydrogels can kill bacteria and help heal tissue using light-converted heat.
9 citations
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June 2020 in “BMC Molecular and Cell Biology” Stress hormone CRF can cause hair loss by affecting hair growth cells and hormones.
13 citations
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July 2014 in “Cell stem cell” Stem cells can be primed to respond faster to injury through mTORC1 signaling, enhancing muscle regeneration.
May 2025 in “Experimental Dermatology” Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.
14 citations
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January 1998 in “Dermatology” Polythelia pilosa is a type of extra breast tissue with hair and should be classified as such.
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January 2015 in “International Journal of Trichology” Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.
November 2022 in “Chinese Journal of Dermatology” Allergies, especially dust mite allergy, may worsen alopecia areata, and desensitization could help reduce its severity.
1 citations
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November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
489 citations
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June 2005 in “The FASEB Journal” Human hair follicles can produce cortisol like the body's stress response system.