85 citations
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July 2012 in “Cold Spring Harbor perspectives in biology” The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
49 citations
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June 2004 in “Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences” Human hair becomes weaker and stretches more easily at higher temperatures.
1 citations
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April 2021 in “Journal of Investigative Dermatology” Activating TRPA1 reduces scarring and promotes tissue regeneration.
87 citations
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March 2007 in “Biological Chemistry” Deleting the scd1 gene in mice prevents obesity by disrupting skin lipids and improving heat regulation.
A new imaging method helps see and study touch nerve endings in mouse skin.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
December 2025 in “Nature Communications” Club-like receptors detect light touch but not whisking.
January 2019 in “Dermatologic Surgery” 56 citations
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January 2014 in “Journal of Investigative Dermatology” Olmsted syndrome can be inherited as an autosomal recessive trait due to a rare TRPV3 gene mutation.
7 citations
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January 2002 in “PubMed” Prolonged UVB exposure causes significant skin changes and damage in rats.
Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
19 citations
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November 2014 in “Journal of Comparative Physiology A” Spider joint hair sensilla are adapted to sense movement during walking.
5 citations
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January 2018 The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
17 citations
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August 1971 in “Journal of Investigative Dermatology”
June 2024 in “Journal of clinical oncology” Scalp cooling can effectively prevent hair loss during chemotherapy, improving patients' quality of life.
May 2025 in “Experimental Dermatology” Triphenylphosphine oxide can increase oil production and reduce inflammation in skin cells without affecting TRPM5.
August 2023 in “ACS applied materials & interfaces” The patch helps heal minor scald wounds by providing electrical and chemical signals to boost recovery.
August 2018 in “Journal of the American Academy of Dermatology” A new cosmetic cream reduced facial redness and skin temperature after 4 weeks of use.
November 2024 in “Journal of the European Academy of Dermatology and Venereology” Cryotherapy with precise temperature control is a promising treatment for alopecia areata.
22 citations
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May 2016 in “Breast cancer research and treatment” Some patients using cold caps to prevent hair loss from chemotherapy got mild scalp injuries similar to frostbite.
13 citations
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January 2018 in “Yonsei Medical Journal” A specific gene mutation causes Olmsted syndrome.
25 citations
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November 2012 in “Thermochimica Acta” Internal lipids in keratin fibers, like wool and hair, reduce water absorption and release.
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
207 citations
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September 1973 in “Entomologia Experimentalis et Applicata” B-type hairs on female butterfly legs help them choose where to lay eggs.
43 citations
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October 2005 in “Molecular and cellular endocrinology” Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
53 citations
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June 1982 in “The BMJ” Cooling the scalp below 22°C before and during chemotherapy can help prevent hair loss.
January 2016 in “Columbia Academic Commons (Columbia University)” Mammalian touch receptors have evolved to detect different features, enhancing our ability to perform various tasks and interact socially.
Sphingosine 1-phosphate helps control mechanical pain.
9 citations
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January 1989 in “Sen'i Gakkaishi” Wool and hair fibers absorb moisture similarly due to their keratin structure, with the amount of non-crystalline areas affecting the moisture uptake.