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Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

A woman experienced severe side effects from a drug due to a specific genetic variation, suggesting genetic testing could prevent such risks.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Budesonide and N-acetylcysteine reduced tumors and alopecia in mice, regardless of FHIT gene status.

The combination of mitoxantrone, etoposide, and prednisolone is effective for treating relapsed lymphoma with manageable side effects.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

A new compound shows promise as a topical treatment for hair loss.

Alloxan diabetes, methylthiouracil, cortisone, and adrenaline affect how white mice hair follicles use glucose and cystine and their cell division.

Arsenic trioxide effectively treats relapsed acute promyelocytic leukemia with manageable side effects.

Eating phenylthiocarbamide made all the rats' hair go gray, but some returned to their original color after stopping.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Azathioprine can cause unexpected hair loss and severe bone marrow issues, so careful monitoring is needed.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

TS-13 effectively stops tumor growth and reduces chemotherapy side effects.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

Mitotane changes steroid breakdown, affecting cortisol availability.

Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.

Natural compounds may help treat advanced papillary thyroid cancer by targeting specific molecular pathways.

Folate may reduce methotrexate side effects in psoriasis patients, but its impact on effectiveness is unclear.

Excessive putrescine causes hair loss in transgenic mice by disrupting hair follicle development.

Methimazole for hyperthyroidism has known and new side effects needing more study for safety.

Methotrexate with steroids is slightly more effective than azathioprine with steroids for treating severe alopecia areata.

Low-dose methotrexate is generally safe but can cause mild to severe side effects, and folic acid can reduce these risks.

Weekly 5 mg folate is enough to prevent methotrexate toxicity in rheumatoid arthritis patients.

Sulfur-containing radioprotectors can protect hair from X-ray damage if given before exposure but worsen damage if given after.

Thymectomy and high-dose prednisolone improved hair loss in a woman with alopecia areata.