research PROTACs: A novel strategy for cancer drug discovery and development
PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.
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30-60 / 1000+ resultsresearch Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
research Marie Krogh's contributions to the study of thyroid physiology and pathophysiology
Marie Krogh advanced understanding of thyroid hormones' effects on metabolism.
research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
research Evaluation of Serum Ferritin, Creatinine and Liver Enzymes in Patients with ß- thalassemia After Administration of Deferasirox
Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.
research Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells
L-threonate may help prevent balding by blocking a key hair loss factor.
research Preventable effect of L-threonate, an ascorbate metabolite, on androgen-driven balding via repression of dihydrotestosteroneinduced dickkopf-1 expression in human hair dermal papilla cells
L-threonate may help prevent balding by blocking a key protein.
research THALLIUM POISONING
Thallium poisoning from contaminated tortillas caused severe symptoms and was mostly fatal or led to long-term health issues.
research Chronische Thalliumintoxikation: Beobachtung einer kriminellen Vergiftung
A man was poisoned with thallium, treated successfully, but still had some nerve issues after 6 months.
research Beta thalassemia revealing hypothyroidism: A case report
Frequent blood transfusions in beta thalassemia can lead to thyroid problems.
research Application of Thulium 1927-nm Laser for Androgenic Alopecia Treatment in Indonesian Patients
Thulium laser therapy is a safe and effective short-term treatment for hair regrowth.
research Application of Thulium 1927-nm Laser for Androgenic Alopecia Treatment in Indonesian Patients.
Thulium laser therapy is a safe and effective short-term treatment for hair regrowth in androgenic alopecia patients.
research The 1,927-nm fractionated thulium laser monotherapy increases hair density in patients with male pattern hair loss in Brazil: prospective clinical study
The laser treatment increased hair density in men with hair loss.
research Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One
Adding a second method to PROTACs could improve cancer treatment.
research Thallium poisoning and emergency care:research advances
Thallium poisoning is serious, affecting nerves and organs, and is treated by reducing absorption and removing it from the body.
research Evaluation of a new X-ray fluorescent analysis technique for the creation of a Nordic hair database: elemental distributions within the root and the virgin segment of hair fibers.
The new X-ray technique allows for precise and non-destructive measurement of elements in hair, creating the first database of its kind for a specific ethnic group.
research SUN-195 Falsely Elevated Testosterone Levels: Role of LC-MS/MS in Reducing Unnecessary Testing
Using LC-MS/MS for hormone measurement can prevent false high testosterone results and avoid unnecessary tests.
research Beta thalassemia revealing hypothyroidism: A case report
Frequent blood transfusions in beta thalassemia patients can lead to thyroid problems.
research Original synthetic monophenolic antioxidant with combined effect inhibits tumor growth in vivo
TS-13 effectively stops tumor growth and reduces chemotherapy side effects.
research Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
research PC-SPES Studies Promising, But Manufacturer Shuts Down
Promising cancer treatments were found, but the manufacturer closed.
research Modeling and Simulation of X-Rays Radiotherapy
Microbeam Radiation Therapy is effective, but using a linear accelerator reduces its benefits.
research Thallium poisoning: emphasis on early diagnosis and response to haemodialysis
Early diagnosis and haemodialysis can effectively treat thallium poisoning.
research Thallium
Thallium exposure can cause serious health issues, including nerve damage and hair loss.
research Steroidomics for highlighting novel serum biomarkers of testosterone doping
Monitoring steroid hormones in blood can better detect testosterone doping.
research Compounded Testosterone Troches TO OPTIMIZE HEALTH AND THE TESTOSTERONE CONTROVERSY.
Properly administered testosterone therapy is safe and effective but often not covered by insurance.
research Global trends in tertiary lymphoid structures: a bibliometric analysis from 2014 to 2023
Tertiary lymphoid structures are important in immunotherapy and need more research.
research A Successfully Treated Case of Criminal Thallium Poisoning
A woman poisoned with thallium was successfully treated with activated charcoal and Prussian blue.
research Phase II trial of paclitaxel poliglumex (CT-2103) in pre- and post-menopausal women on hormonal replacement therapy (HRT) with non-small cell lung cancer (NSCLC).
Further testing of paclitaxel poliglumex for this cancer treatment is not justified.
research Emerging Strategies in Smart Nano-PROTAC for Stimuli-Responsive Protein Degradation and Precision Cancer Therapy
Smart nano-PROTACs improve cancer treatment by targeting proteins more precisely and reducing side effects.