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Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Many COVID-19 survivors experience long-term symptoms like fatigue and sleep issues, needing ongoing medical support.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

The document concludes with guidance for doctors on diagnosing and treating hirsutism effectively and safely.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Using steroids can increase the risk of heart problems.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Hormonal changes during and after pregnancy can cause hair growth changes and hair loss, with treatments available for some conditions.

Blocking enzymes that help the virus enter cells could be a promising way to treat COVID-19.

Tamoxifen caused hair loss in a 52-year-old woman.

Platelet-rich treatments can help improve wound healing and tissue repair.

Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

Testosterone may both worsen and protect against COVID-19 effects in men.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

Hormonal therapies, like flutamide and cyproterone acetate, are safe and effective for treating adult women's acne, especially those with hormone imbalance or resistant acne.

A woman had hair loss, nail changes, and skin peeling after a COVID-19 infection, which got better on their own.

Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.

Women with alopecia may have a higher chance of getting thyroid cancer.