14 citations
,
February 2007 in “Irish Veterinary Journal” A dog with a pituitary tumor developed tertiary hypothyroidism, improved with treatment, but was later euthanized due to neurological issues.
21 citations
,
April 2019 in “Journal of cutaneous pathology” People with alopecia areata have fewer regulatory T-cells than those with other skin conditions.
3 citations
,
January 2013 Hypothyroidism in dogs is usually caused by immune system issues or gland atrophy, affects middle-aged purebreds most, and is treatable with medication.
6 citations
,
March 2005 in “Journal of the American Academy of Dermatology” Follicular dystrophy in immunocompromised patients may be linked to medication or viral factors and can improve with treatment changes.
January 2025 in “Mansoura Medical Journal” TPO antibodies can help identify hypothyroid patients who still have symptoms despite normal TSH levels.
January 2009 in “Journal of the American Academy of Dermatology” Generalized trichoepitheliomas with alopecia may indicate myasthenia gravis.
October 2024 in “Journal of the Endocrine Society” Acute illnesses like sepsis can disrupt thyroid hormone balance without central hypothyroidism.
October 2025 in “Journal of Skin and Sexually Transmitted Diseases” Alopecia areata patients often have undetected thyroid issues, so routine thyroid screening is recommended.
December 2019 in “Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü dergisi” One cat with low thyroid hormone had growth issues, and another with high thyroid hormone had skin problems; both got better with treatment.
December 2009 in “생명과학회지” Thymosin β4 and VEGF are important for organ function and may help with blood vessel formation.
14 citations
,
January 2012 in “International Journal of Trichology” Hodgkin's lymphoma can show up as hair loss.
2 citations
,
July 2012 in “InTech eBooks” People with alopecia areata often have thyroid autoimmunity.
Thymosin β4 helps with healing, inflammation, and organ protection.
5 citations
,
March 2016 in “Experimental and molecular pathology” Mice with alopecia areata had wider lymphatic vessels in their skin.
February 2026 in “International Journal of Advanced Biochemistry Research” Hypothyroidism-related skin issues in dogs are most common in older male Labradors, causing hair loss, slow heart rate, and obesity.
January 2024 in “Inflammation and regeneration” Th22 cells are essential for Tβ15-induced hair growth in mice.
5 citations
,
May 2007 in “Pediatric Dermatology” Severe hypothyroidism can cause unusual skin problems that improve with thyroid treatment.
July 2024 in “Journal of Investigative Dermatology”
1 citations
,
January 2015 in “Advanced techniques in biology & medicine” Down Syndrome patients with Alopecia Areata often have hypothyroidism and specific immune abnormalities.
14 citations
,
July 2021 in “Bioscience Reports” Activating Tgr5 may help treat hair loss and bone loss.
6 citations
,
January 2013 in “IOSR Journal of Dental and Medical Sciences” Most people with hypothyroidism have skin problems like dry skin and hair loss.
11 citations
,
January 1973 in “BMJ” Primary hypothyroidism can mimic pituitary failure but improves with hormone therapy.
21 citations
,
February 2012 in “Journal of the European Academy of Dermatology and Venereology” Late-onset alopecia areata in Taiwanese patients is more common in women, usually starts at age 57, often involves less than 10% hair loss, and may have a minimal link to thyroid issues.
April 2023 in “Journal of Investigative Dermatology” Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
2 citations
,
April 2015 in “Journal of Evolution of Medical and Dental Sciences” Most hypothyroid patients experience dry skin and swelling.
21 citations
,
December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
November 2024 in “Malaysian Journal of Microbiology” Patients with thyroid disorders show different symptoms and antibody levels.
23 citations
,
July 2022 in “Nature Cell Biology” Targeting THY1 can improve skin repair and healing.
5 citations
,
June 2022 in “Frontiers in immunology” Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.
1 citations
,
January 2013 in “INTAS POLIVET” The Labrador dog fully recovered from hypothyroidism after 3 months of treatment.