research Plasticity of epithelial stem cells in tissue regeneration
Epithelial stem cells can adapt and help in tissue repair and regeneration.
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research Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche
Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
research Eavesdropping on the conversation between immune cells and the skin epithelium
Immune cells help keep skin healthy and repair it, but imbalance can cause disease.
research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research Advances in single-cell transcriptomics in animal research
Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
research Hair regrowth in alopecia areata patients following Stem Cell Educator therapy
Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
research The role of PEDF in ageing and development: reduction of oxidative damage and support for stem cells
PEDF reduces oxidative damage and supports stem cells.
research Tracking adult stem cells
A combined approach is needed to fully understand adult stem cells, with genetic lineage-tracing being crucial.
research CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice
CD34 is crucial for skin tumor development in mice.
research UVB-induced depletion of donor-derived dendritic cells prevents allograft rejection of immune-privileged hair follicles in humanized mice
UV light helped human hair transplants survive in mice without broad immunosuppression.
research Human Dermal Fibroblasts Demonstrate Positive Immunostaining for Neuron- and Glia- Specific Proteins
Fibroblasts can be mistaken for neural cells, so functional validation is needed.
research Therapeutic small extracellular vesicles from key human stem and immune cellular sources: A review
Small extracellular vesicles from stem and immune cells show promise for treating various diseases but face challenges in clinical use.
research Matriptase: Potent Proteolysis on the Cell Surface
Matriptase is crucial for skin, hair, and immune cell health, and its imbalance can lead to cancer.
research Physiologic functions of PP2A: Lessons from genetically modified mice
Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.
research Regulatory Mechanisms of Natural Active Ingredients and Compounds on Keratinocytes and Fibroblasts in Mitigating Skin Photoaging
Natural ingredients may help reduce skin aging by protecting cells and boosting collagen.
research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity
Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.
research Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis
Hair follicle cells need complex interactions to fully differentiate.
research A Two-Stepped Culture Method for Efficient Production of Trichogenic Keratinocytes
A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.
research Clinicopathological Features and Pathogenesis of Thymoma Complicated with Alopecia Areata: A Multicenter, Matched Case Analysis
Thymoma with alopecia areata may be linked to abnormal immune cells.
research A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus
Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
research Sonic Hedgehog signalling in the regulation of barrier tissue homeostasis and inflammation
Sonic Hedgehog helps keep skin and airway barriers healthy and reduces inflammation.
research Effects of hyperbaric oxygen therapy on rat facial skin
Hyperbaric oxygen therapy significantly altered rat facial skin structure.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research A Systematic Review of Keratinocyte Secretions: A Regenerative Perspective
Skin cells release substances important for healing and fighting infection, and understanding these could improve skin disorder treatments.
research Exosomal microRNA-Based therapies for skin diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
research Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Type 2 immunity helps control mite growth in hair follicles, preventing damage.
research From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology
JAK inhibitors are effective for treating moderate-to-severe alopecia areata.
research Referee report. For: Advances in Understanding Hair Growth [version 1; referees: 3 approved]
Glycans play a crucial role in regulating hair growth and follicle balance.
research Referee report. For: Advances in Understanding Hair Growth [version 1; referees: 3 approved]
Glycans play a crucial role in regulating hair growth and follicle balance.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.