January 2005 in “Elektronische Hochschulschriften der LMU München (Ludwig-Maximilians-Universität München)” Topical immunotherapy with DPCP is most effective for certain alopecia areata types, with success linked to age and disease duration, and influenced by a gene polymorphism.
Amotosalen-treated donor T-cells can prevent late CMV infection after bone marrow transplants.
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April 2017 in “Journal of Dermatological Science” Certain immune cells may cause hair loss by reacting to stressed hair follicles.
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July 2001 in “Proceedings of the National Academy of Sciences” TGFβ1 expression in skin causes hair loss and skin thickening, but these effects are reversible.
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July 2001 in “The FASEB Journal” Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.
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April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
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July 2015 in “PloS one” Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.
November 2025 in “Stem Cell Research & Therapy” Human hair follicle cells can help regenerate hair and reduce inflammation, aiding in hair loss treatment.
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November 2012 in “European Journal of Cell Biology” The authors clarified data overlap and corrected a figure error, apologizing for any confusion.
December 2023 in “Communications biology” Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
April 2018 in “Journal of Investigative Dermatology” Id2 gene helps keep hair follicle stem cells inactive.
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
August 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.
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August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
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May 2005 in “Expert Review of Clinical Immunology” Blocking interferon-gamma might help treat various autoimmune diseases.
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February 2010 in “Endocrinology” The skin produces and responds to thyroid-stimulating hormone, which is controlled by other thyroid-related hormones.
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September 2017 in “Stem cell investigation” PDGF signaling is crucial for maintaining fat stem cells in the skin, and its level of activation can either preserve these cells or cause fibrosis.
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October 2001 in “Dermatologic Clinics” The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.
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January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
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June 2011 in “Journal of Neuroscience” p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
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April 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicles help skin immune recovery after UVB exposure.
January 2017 in “Journal of clinical & experimental dermatology research” Scientists have found a way to create hair follicles from human stem cells, which could potentially be used to treat hair loss.
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April 2005 in “Journal of Investigative Dermatology” Human hair follicle cells can become fat and bone cells, useful for therapy.
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May 2018 in “International Journal of Molecular Sciences” The research showed how melanocytes develop, move, and respond to UV light, and their stem cells' role in hair color and skin cancer risk.
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January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
October 2022 in “The American journal of gastroenterology” Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.
April 2017 in “Journal of Investigative Dermatology” Blood cells turned into stem cells can become skin cells similar to normal ones, potentially helping in skin therapies.
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March 2013 in “Expert opinion on biological therapy” Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
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August 2019 in “Frontiers in immunology” Tyrosine kinases are important in skin autoimmune diseases and could be targets for new treatments.