April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.
8 citations
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September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” CTCF protein is essential for skin and hair follicle development in mice.
83 citations
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May 2022 in “Journal of Advanced Research” Enhancing glycolysis in mesenchymal stromal/stem cells boosts their immune functions and therapy potential.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
6 citations
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November 2021 in “Frontiers in immunology” STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.
June 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In alopecia areata, certain immune cells increase and express a protein linked to immune activation.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
22 citations
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June 2010 in “Experimental Dermatology” Lower MC2R expression may contribute to alopecia areata.
33 citations
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June 2007 in “Gene Expression Patterns” CTIP2 may help in skin development and maintenance.
17 citations
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June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
2 citations
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January 2014 in “Journal of Cytology & Histology” Rapamycin and anti-EGFR antibody reduce LAM/TSC cell migration and blood vessel growth in the uterus.
53 citations
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April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
68 citations
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December 1983 in “British Journal of Dermatology” Major histocompatibility antigens are found in specific skin cells and structures, but not in sweat glands.
13 citations
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July 2014 in “Cell stem cell” Stem cells can be primed to respond faster to injury through mTORC1 signaling, enhancing muscle regeneration.
1 citations
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January 1989 in “Carcinogenesis” Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
33 citations
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May 2018 in “Stem Cell Reports” Krt15+ cells in the mouse intestine resist radiation and can start tumors.
31 citations
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June 2011 in “Journal of the neurological sciences” Removing the thymoma improved the man's autoimmune conditions.
November 2025 in “Clinical Cosmetic and Investigational Dermatology” Immune cells and plasma proteins are linked to hair loss, suggesting new treatment options.
60 citations
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October 2020 in “Nature Communications” AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.
April 2023 in “Journal of Investigative Dermatology” Contact immunotherapy can change immune responses in alopecia areata, suggesting new treatment targets.
13 citations
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July 1994 in “PubMed” Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.
43 citations
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May 1999 in “Journal of Biological Chemistry” Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
CAR-T cell therapy shows promise for treating autoimmune disorders but faces challenges like complex manufacturing and limited tissue penetration.
3 citations
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January 2014 in “International Journal of Medical Sciences” Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.
June 2015 in “Han'gug eung'yong saengmyeong hwa haghoeji/Journal of the Korean Society for Applied Biological Chemistry” Some synthesized peptides improved cell growth better than thymosin β4, VEGF, and minoxidil.
Thymosin β4 helps heal corneal wounds.
1 citations
,
July 2024 in “Journal of Investigative Dermatology” TAK-279 effectively reduces psoriasis symptoms and is safe.
96 citations
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March 2003 in “Life Sciences” Atopic dermatitis patients have much higher acetylcholine levels in their skin, which may cause itching.