L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
January 2017 in “Clinical approaches and procedures in cosmetic dermatology” Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.
32 citations
,
March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
30 citations
,
October 2016 in “Current research in translational medicine” Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.
27 citations
,
September 2014 in “JAMA dermatology” Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.
21 citations
,
December 2007 in “Primary Care” Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
April 2024 in “International Journal of Advanced Multidisciplinary Research and Studies” Early investigation and a team approach are crucial for managing primary amenorrhea effectively.
October 2023 in “Dermatology practical & conceptual” Many patients experienced hair loss after COVID-19, with women affected more, starting on average 49 days post-infection.
January 2023 in “Pakistan Armed Forces Medical Journal”
January 2023 in “Scholars journal of applied medical sciences” The main causes of hirsutism in Jordanian women are PCOS and idiopathic hirsutism.
January 2015 in “Springer eBooks” The document concludes that managing PCOS involves lifestyle changes, medication, and monitoring for associated health risks.
May 2010 in “Current Women's Health Reviews” The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
218 citations
,
December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
99 citations
,
July 2017 in “Clinical Reviews in Allergy & Immunology” New treatments for Alopecia Areata show promise but need to be more effective and affordable.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
71 citations
,
January 2015 in “The Scientific World Journal” Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.
54 citations
,
December 2007 in “Best Practice & Research Clinical Endocrinology & Metabolism” Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.
54 citations
,
January 2005 in “Journal of The American Academy of Dermatology” Most patients with chronic hair shedding did not progress to permanent hair loss, and one showed improvement with treatment.
27 citations
,
August 2014 in “Wiley interdisciplinary reviews. Developmental biology” The skin and thymus develop similarly to protect and support immunity.
11 citations
,
January 2015 in “Current problems in dermatology” The conclusion is that treatments like finasteride and minoxidil can prevent baldness progression and improve hair density, but more research is needed on other therapies.
10 citations
,
November 2018 in “Physiological Research” The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.
9 citations
,
September 2019 in “Journal of Cosmetic Dermatology” PRP injections improve hair density in male hair loss.
6 citations
,
July 2013 in “Acta Clinica Belgica” The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.
4 citations
,
March 2021 in “Case Reports” A woman's excessive hair growth and masculine features were due to a rare benign ovarian tumor and endometrial cancer, which improved after surgery.
4 citations
,
October 2019 in “Skin appendage disorders” PRP injections safely increase hair density and thickness in androgenetic alopecia.
2 citations
,
August 2014 in “Archivos argentinos de pediatría” A 6-year-old girl with Turner syndrome also had psoriasis, alopecia areata, and trachyonychia.
1 citations
,
September 2025 in “Dermatology and Therapy” GLP-1 RAs help with diabetes and skin issues but can cause skin reactions and surgery challenges.
June 2025 in “Mağallaẗ ʻulūm al-rāfidayn” New pyrazole derivatives may help treat hair loss, but more testing is needed.
Orthognathic surgeons play a key role in modifying masculine facial features to be more feminine, often improving transgender women's quality of life.