November 2023 in “Journal of the American Society of Nephrology” This document discusses the care considerations and management of transgender individuals after kidney transplantation, highlighting two cases from a single institution. The first case involves a 48-year-old trans-female who experienced gender dysphoria post-transplant and began gender-affirming care, which improved her mental health and medication adherence while maintaining stable renal function. The second case is a 57-year-old trans-male who sought gender-affirming care post-transplant, leading to polycythemia and osteoporosis, but also maintained stable renal function and good medication adherence. The discussion emphasizes the complexities of managing transgender patients post-transplant, including the risks associated with hormone therapy, such as thromboembolic events, hyperkalemia, polycythemia, and urological complications from surgeries. It underscores the importance of regular screenings for osteoporosis and sexually transmitted infections, as well as providing psychotherapeutic support. Additionally, it recommends using a non-sex-dependent estimation of GFR due to the effects of hormone therapy on muscle mass and body composition.
September 2023 in “Journal of the American Academy of Dermatology” Methylprednisolone treatment helps most alopecia areata patients, but young age, extensive hair loss, and low vitamin D can affect results.
February 2022 in “Endocrine connections” People with reproductive, thyroid disorders, and type 2 diabetes can experience voice changes, but more research is needed to understand this better.
November 2022 in “Journal of the Endocrine Society” A woman with ectopic Cushing's syndrome and COVID-19 passed away despite treatment.
January 2024 in “International Journal of Medicine in Developing Countries” Most people in Alahsa, Saudi Arabia, have low awareness of thyroid disease symptoms and risk factors.
18 citations
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October 1986 in “PubMed” Alpha-tocopherol does not prevent hair loss from doxorubicin.
May 2022 in “Experimental dermatology” Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
17 citations
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April 2009 in “Andrologia” A boy's early puberty caused by a testicular tumor returned to normal after surgery.
2 citations
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April 2023 in “Pharmaceuticals” Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
21 citations
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December 2012 in “Maturitas” Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
February 2016 in “PubMed” Properly administered testosterone therapy is safe and effective but often not covered by insurance.
5 citations
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October 2018 in “Dermatologic therapy” Recognizing congenital triangular alopecia is crucial to avoid unnecessary treatments.
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November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.
22 citations
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November 1979 in “Archives of dermatology” A woman with Fox-Fordyce disease had symptom relief using tretinoin cream.
January 2016 in “Dermatology Online Journal” Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.
January 2025 in “LUMEN ET VIRTUS” Orchiectomy and melatonin helped a German Spitz regrow hair lost due to alopecia X.
1 citations
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January 2017 in “Yonsei Medical Journal” Hair is thinner near the scalp in acute hair shedding conditions.
1 citations
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January 1989 in “Carcinogenesis” Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
45 citations
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March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.
1 citations
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August 2024 in “SAR Journal of Pathology and Microbiology” Many Iraqi women with hirsutism also have hypothyroidism and acne.
May 2023 in “The journal of sexual medicine” Ovarian Hyperthecosis caused hypersexuality in an older woman and was successfully treated with surgery.
November 2017 in “Reactions Weekly” Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.
January 2020 in “Animal Husbandry Dairy and Veterinary Science” Tetracycline successfully treated a Labrador's skin calcification and hair loss.
January 2009 in “Epsilon: Revista de la Sociedad Andaluza de Educación Matemática "Thales"” A CCS patient with severe complications was successfully treated using combined therapies.
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.
April 2019 in “Journal of the Endocrine Society” A woman's severe male-like symptoms were caused by a rare, benign tumor in her ovary that produced male hormones.
166 citations
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October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
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August 2016 in “Journal of the European Academy of Dermatology and Venereology” Oral tacrolimus helped a rheumatoid arthritis patient regrow hair lost due to alopecia areata.
14 citations
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June 2016 in “PubMed” Regular lab tests and follow-ups are important for managing vitiligo, especially checking thyroid antibodies.
November 2022 in “Journal of the Endocrine Society” Diagnosing osteoporosis in transgender people is challenging due to unclear guidelines and hormone treatment effects.