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research 586 Increase in CD8+ effector memory cells re-expressing CD45RA (TEMRA) reflects disease activity and enables early prediction of therapeutic outcome in rapidly progressive alopecia areata

April 2023 in “Journal of Investigative Dermatology”

Increased TEMRA cells can predict treatment outcomes in rapidly progressive alopecia areata.

research Dicer- and Bulge Stem Cell-Dependent MicroRNAs During Induced Anagen Hair Follicle Development

10 citations , May 2020 in “Frontiers in cell and developmental biology”

MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.

research Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells.

October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Activating telomerase can boost hair follicle stem cell growth and hair production.

research Identification of a preferred substrate peptide for transglutaminase 3 and detection of in situ activity in skin and hair follicles

35 citations , July 2010 in “The FEBS journal”

The study found a specific peptide that helps detect TGase 3 activity in skin and hair follicles.

research DEFINING THE ROLE OF ABI1 GENE IN PROSTATE CANCER PROGRESSION AND TREATMENT RESISTANCE

January 2024 in “Wiadomości Lekarskie”

The ABI1 gene contributes to prostate cancer progression and treatment resistance.

research The function of TRPS1 in the development and differentiation of bone, kidney, and hair follicles.

52 citations , July 2011 in “PubMed”

TRPS1 is crucial for bone, kidney, and hair follicle development.

research Transcriptional regulation analysis and the potential transcription regulator site in the extended KAP6.1 promoter in sheep

5 citations , July 2014 in “Molecular Biology Reports”

research Protease-Activated Receptor-1 (Thrombin Receptor) Is Expressed in Mesenchymal Portions of Human Hair Follicle

7 citations , September 2003 in “Journal of Investigative Dermatology”

PAR-1 may play a role in hair growth regulation in human hair follicles.

research Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth

85 citations , June 2017 in “Journal of Investigative Dermatology”

Blimp1 is crucial for hair follicle growth and skin health.

research Trichocyte Keratin-Associated Proteins (KAPs)

17 citations , January 2018 in “Advances in experimental medicine and biology”

research Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia

19 citations , August 2012 in “Cell death and differentiation”

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation

321 citations , January 2012 in “Cell stem cell”

TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.

research The clock gene brain and muscle Arnt-like protein-1 (BMAL1) is involved in hair growth

9 citations , August 2013 in “Archives of Dermatological Research”

A gene called BMAL1 plays a role in controlling hair growth.

research Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury

12 citations , October 2017 in “Radiation Research”

mTORC1 signaling needed for quick hair follicle recovery after radiation damage.

research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells

10 citations , June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

FP-1 is a key protein in rat hair growth, active only during the growth phase.

research The role of Twist1 in UVB-induced skin carcinogenesis

December 2020

Deleting Twist1 in skin cells reduces UVB-induced skin cancer risk.

research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt^WT mice

8 citations , September 2013 in “Molecular carcinogenesis”

Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.

research Dicer- and BSC-dependent miRNAs during murine anagen development

1 citations , January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Dicer is crucial for hair growth in mice.

Knockout of Integrin Beta1 in Induced Pluripotent Stem Cells Accelerates Skin-Wound Healing by Promoting Cell Migration in Extracellular Matrix

research Knockout of integrin β1 in induced pluripotent stem cells accelerates skin-wound healing by promoting cell migration in extracellular matrix

3 citations , July 2022 in “Stem Cell Research & Therapy”

Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.

research Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1

333 citations , March 2000 in “Proceedings of the National Academy of Sciences”

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

research Topical tacrolimus suppresses the expression of vascular endothelial growth factor and insulin-like growth factor-1 in late anagen

6 citations , June 2009 in “Clinical and Experimental Dermatology”

Topical tacrolimus reduces certain growth factors in hair follicles.

research Message of nexin 1, a serine protease inhibitor, is accumulated in the follicular papilla during anagen of the hair cycle

37 citations , December 1995 in “Journal of Cell Science”

Nexin 1 may help control hair growth.

research TRPS1 haploinsufficiency results in increased STAT3 and SOX9 mRNA expression in hair follicles in trichorhinophalangeal syndrome

2 citations , September 2016 in “Journal of Dermatological Science”

Reduced TRPS1 leads to increased STAT3 and SOX9 in hair follicles, affecting hair growth.

research Polymorphisms and association of FAT1 gene with wool quality traits in Chinese Merino sheep

6 citations , January 2020 in “Czech Journal of Animal Science”

The FAT1 gene and its variations can help improve wool quality in Chinese Merino sheep through selective breeding.

research Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis

7 citations , August 2022 in “Nature communications”

A specific group of slow-growing stem cells marked by Thy1 is crucial for skin maintenance and healing in mice.

research Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling

475 citations , October 2006 in “Proceedings of the National Academy of Sciences”

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

research Post-tyrosinase Inhibition of Melanogenesis by Melatonin in Hair Follicles in Vitro

75 citations , January 1980 in “Journal of Investigative Dermatology”

research Expression of nicastrin, NICD1, and Hes1 in NCSTN knockout mice: implications for hidradenitis suppurativa, Alzheimer’s, and liver cancer

December 2024 in “European journal of medical research”

research Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration

30 citations , February 2017 in “Histochemistry and Cell Biology”

TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.

research lncRNA2919 Suppresses Rabbit Dermal Papilla Cell Proliferation via trans-Regulatory Actions

4 citations , August 2022 in “Cells”

lncRNA2919 slows down rabbit hair growth by stopping cell growth and causing cell death.

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