35 citations
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January 2000 in “Journal of comparative neurology” Rat vibrissae have sensory terminals with specific structures that help detect hair movements.
26 citations
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December 2015 in “International Journal of Dermatology” Trichodynia is a painful scalp condition linked to hair loss and inflammation, often with anxiety, affecting more women and needing better treatment options.
6 citations
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September 2021 in “Experimental Brain Research” Rats have different touch receptors in their paws that help with movement and handling objects.
July 2023 in “Cosmoderma” 660 citations
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December 2011 in “Cell” Different hair follicles in the skin are innervated by unique combinations of mechanosensory neurons, crucial for touch sensation.
September 2023 in “Journal of the American Academy of Dermatology” Oral difelikefalin significantly reduces itch in notalgia paresthetica.
24 citations
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March 2008 in “Neuroscience Research” Cat paws have complex touch sensors for detailed sensory processing.
August 2020 in “Bioscience Biotechnology Research Communications” Topical anaesthesia reduces injection pain better than a vibrating device.
110 citations
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January 1983 in “Brain Research Reviews” Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
2 citations
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August 2019 in “Electronics and Communications in Japan” The device mimics human hair follicles and detects tiny forces and moments with high sensitivity.
28 citations
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January 2010 in “Biological & pharmaceutical bulletin” Certain essential oils can activate a human skin receptor, potentially helping with skin disorders.
September 2025 in “PubMed” Auricular electrostimulation reduces itching in mice.
1 citations
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January 2022 in “Dermatology Reports” Many people with hair loss, especially those with telogen effluvium and alopecia areata, often have a sensitive scalp.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
46 citations
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July 2007 in “Journal of comparative neurology” Manatee whiskers are specially adapted for touch in water.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The back of the scalp has more nerve fibers than the front, which may explain why some people feel more sensitivity there.
41 citations
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April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.
123 citations
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November 2003 in “Neuroscience Letters” TRPV4 helps sense pressure in mouse skin.
April 2017 in “InTech eBooks” Many people with hair loss experience scalp pain known as trichodynia, but the causes are unclear and treatments vary.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” T cells with memory features grow in number and gather around hair follicles when there are not enough immune cells.
15 citations
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July 1968 in “JAMA” Severe itching can be an early sign of hyperthyroidism.
101 citations
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August 2003 in “Journal of comparative neurology” Naked mole-rats have unique skin and hair nerve structures, lacking certain pain and temperature-related neuropeptides.
November 2025 in “Journal of Investigative Dermatology” 11 citations
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July 1968 in “JAMA” Itching can be an early sign of hyperthyroidism.
March 2005 in “Journal of The American Academy of Dermatology” Itch is a common symptom in patients with chronic venous insufficiency, often worsening with standing or sitting and occurring mostly in the evening or at night.
109 citations
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April 1997 in “Archives of Dermatological Research” Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
1 citations
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June 2019 in “IEEJ Transactions on Sensors and Micromachines” A new device mimics hair follicle functions and detects tiny forces with high sensitivity.
1 citations
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January 1996 in “Aesthetic Plastic Surgery” The tumescent technique makes hair micrografting more comfortable and efficient.
March 2005 in “Journal of The American Academy of Dermatology” Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.