551 citations
,
November 2013 in “Nature” Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.
417 citations
,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
355 citations
,
August 2013 in “Acta Biomaterialia” The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.
294 citations
,
January 2016 in “Stem Cells International” Adipose-derived stem cells are promising for tissue and organ repair due to their easy access and versatility.
265 citations
,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
262 citations
,
May 2017 in “Nanomedicine” New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
238 citations
,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
211 citations
,
April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
182 citations
,
June 2017 in “Biomaterials” Special fiber materials boost the healing properties of certain stem cells.
162 citations
,
July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
140 citations
,
August 2011 in “Biomaterials” Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
130 citations
,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
126 citations
,
January 1987 in “Journal of The American Academy of Dermatology” The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.
119 citations
,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.
115 citations
,
November 2004 in “Brain Behavior and Immunity” Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
99 citations
,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
75 citations
,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
71 citations
,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
71 citations
,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
71 citations
,
March 1995 in “Journal of The American Academy of Dermatology” Using both vertical and transverse sections for alopecia biopsies improves diagnosis without extra cost.
70 citations
,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
61 citations
,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
60 citations
,
June 2019 in “Ageing Research Reviews” Fat from the body can help improve hair growth and scars when used in skin treatments.
51 citations
,
May 2021 in “Nature Communications” High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
48 citations
,
December 2004 in “Differentiation” Tooth papilla cells can help regenerate hair follicles and grow hair.
47 citations
,
July 2013 in “Pharmacological Reviews” Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.