14 citations
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October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
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October 2005 in “PubMed” Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
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July 2025 in “Biomaterials Advances” 3D cultures respond better to minoxidil, while 2D cultures respond better to DHT.
Loss of Dnmt3a and Dnmt3b leads to more aggressive skin tumors, but blocking PPAR-γ can reduce this effect.
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December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
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August 2025 in “Epigenetics & Chromatin” H3K4me3 helps control RSPO3 to influence hair growth and development.
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July 2012 in “Journal of Investigative Dermatology” Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.
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April 2017 in “Plastic and reconstructive surgery. Global open” Baby and adult skin cells are different, with baby cells having more active pathways that could help grow new hair follicles.
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December 2008 in “PubMed” Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.
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March 2024 in “Cells” MiR-23b and miR-133 affect sheep hair growth by targeting specific genes.
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July 2006 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone increases hair follicle cell growth when beard or axillary skin cells are present together.
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October 2010 in “Stem Cells” Hair follicle stem cells can help treat eye surface issues by becoming corneal cells.
MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
January 2005 in “Journal of Shandong Univenity” Epidermal stem cells are in hair follicle bulge regions, and isolation and culture methods are effective.
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July 1990 in “Acta Dermato Venereologica” High levels of testosterone and dihydrotestosterone inhibit hair cell growth, while high levels of estradiol promote it.
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September 2008 in “Biochemical and Biophysical Research Communications” Hair follicles can be used to easily create neurons and glial cells for potential nerve repair.
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January 2007 in “Dermatology” Scientists have made progress in understanding hair follicle stem cells, identifying specific genes and markers, and suggesting their use in treating hair and skin conditions.
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January 2015 in “World Journal of Stem Cells” Hair follicle regeneration needs special conditions and young cells.
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June 2008 in “Cell Cycle” Hair follicle stem cells can help repair spinal cord injuries and improve walking.
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October 2006 in “Molecular and Cellular Endocrinology” The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
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March 2015 in “Journal of dermatology” The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.
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June 2011 in “Journal of Neuroscience” p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
August 2024 in “Archives of Dermatological Research” CHI3L1 and CXCL5 proteins help promote hair growth.
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April 2013 in “PLoS ONE” Thymosin Beta 4 helps human dental pulp cells develop into tooth-forming cells, suggesting it could aid dental regeneration.
July 2022 in “Institutional Repositories DataBase (IRDB)” 3D spheroid cells effectively test hair growth compounds like Minoxidil.
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March 2023 in “Molecular Therapy — Nucleic Acids” Mechanical stimuli and CCL2 can help regenerate hair follicles in adult mice.
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February 1989 in “Journal of Cutaneous Pathology” A unique hair tumor with a rippled pattern was identified, showing incomplete differentiation and unusual cell arrangements.
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February 2007 in “Molecular Carcinogenesis” Overexpressing ATF3 in mice's epithelial cells may lead to oral cancer.