Spiny mice have resilient, large mitochondria that help them regenerate tissue.
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June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Hair follicle stem cells can generate all hair cell types, skin, and sebaceous glands.
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January 2018 in “Scientific reports” Bioluminescence imaging can track hair follicle cells and help study hair regrowth.
April 2026 in “Scientific Reports” Capillary and dermal papilla interactions are vital for hair growth and aging, with potential for treating hair loss.
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February 2011 in “Cell” Nephronectin helps attach muscle cells to hair follicles.
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December 2014 in “PLoS ONE” A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.
April 2023 in “Journal of Investigative Dermatology” Aging changes skin cells, leading to different DNA methylation and gene activity, affecting cell metabolism and aging signs.
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February 2008 in “Archives of Dermatological Research” Mast cells might contribute to hair loss by causing skin thickening.
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July 2019 in “Journal of Dermatological Science” Increasing alkaline phosphatase in human skin cells helps to grow more hair.
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October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
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January 2019 in “Annals of dermatology/Annals of Dermatology” STAT5 is crucial for hair growth in 3D cultured human dermal papilla cells.
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February 2013 in “British Journal of Dermatology” Thyrotropin-releasing hormone may help control skin and hair growth and could aid in treating related disorders.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
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December 2002 in “The Journal of Clinical Endocrinology & Metabolism” Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.
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May 2020 in “Nature Communications” Adult fibroblasts help heart cells mature and improve heart function.
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November 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Different melanocyte types in hair follicles either survive or die during the catagen phase.
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December 2018 in “Frontiers in Endocrinology” Differences in androgen receptor expression and tissue properties may lead to higher cryptorchidism risk in certain rats.
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April 1979 in “Journal of Cutaneous Pathology” Giant cells found in some male pattern baldness cases may help diagnose it and suggest hair is mistakenly seen as foreign by the body.
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September 2010 in “Nucleic acids research” Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
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March 2023 in “Molecular Therapy — Nucleic Acids” Mechanical stimuli and CCL2 can help regenerate hair follicles in adult mice.
July 2025 in “Journal of Investigative Dermatology” Researchers created long-lasting, diverse skin organoids from mouse hair follicle stem cells, useful for studying skin.
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July 2025 in “Biomaterials Advances” 3D cultures respond better to minoxidil, while 2D cultures respond better to DHT.
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August 2013 in “Journal of Investigative Dermatology” Human skin cells can create new hair follicles when transplanted into mice.
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March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.
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January 2015 in “Stem cells international” Human hair follicle stem cells can be turned into red blood cells.
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June 2001 in “British Journal of Dermatology” c-Myc, Max, and Bin1 help hair follicle cells mature and die.
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August 2021 in “Aging” Collagen and TGF-β2 help maintain hair cell shape and youthfulness.
February 2022 in “Research Square (Research Square)” LGR5 is a marker found in hair follicle stem cells in various species and is important for hair growth and skin repair.
January 2006 in “Chinese Journal of Dermatology” Cultured dermal papilla cells can regenerate hair follicles and sustain hair growth.