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ERG increases SOX9, promoting prostate cancer growth and invasion.

A prostate cancer drug can lower the levels of a protein that the coronavirus uses to enter lung cells.

Enzalutamide, a prostate cancer drug, may help prevent COVID-19 by blocking the virus from entering lung cells.

The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.

Low testosterone may indicate severe COVID-19 in men.

COVID-19 may harm male fertility and damage the reproductive system.

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Anti-androgens might help reduce COVID-19 severity in men.

Men have worse COVID-19 outcomes than women due to genetic and hormonal differences.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Men may be more vulnerable to severe COVID-19 due to genetic and hormonal factors, but more research is needed.

Extracellular vesicles and androgen receptors may help identify prostate cancer resistance and reduce SARS-CoV-2 infection.

People with androgenetic alopecia may have a higher risk of severe COVID-19.

Possible link between COVID-19 and hair loss; more research needed.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

Sex hormones may affect COVID-19 severity and outcomes.

COVID-19 can cause various skin lesions, which may result from the virus and immune response, and are not directly linked to illness severity.

Matriptase-2 helps control iron levels by suppressing hepcidin, and its deficiency can cause iron-deficiency anemia.

A certain genetic variant in the androgen receptor may predict the severity of COVID-19 in men.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

Mutations in certain receptors can cause diseases and offer new treatment options.

Dutasteride and finasteride affect different cell types differently.

Certain Dibenzo derivatives may help treat prostate cancer.

Some dibenzo compounds might help treat cancer with fewer side effects.