17 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
May 2012 in “Scientific American” Blocking a compound called prostaglandin D₂ might help treat hair loss.
5 citations
,
July 2003 in “Drug Development Research” Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
2 citations
,
October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” The botanical treatment for hair loss shows promise, especially for children.
211 citations
,
February 2009 in “European journal of pharmaceutics and biopharmaceutics” Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.
5 citations
,
December 2011 in “Drug Research” CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
June 2026 in “Dermatology and Therapy” Combining multiple ingredients is the most effective treatment for hyperpigmentation.
March 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)” Lipid nanoparticles show promise for delivering alopecia treatments to the skin.
14 citations
,
March 2018 in “Current Drug Delivery” Topical finasteride can effectively treat male pattern baldness with fewer side effects than oral use.
January 1985 in “Clinical research” Topical alpha-terthienyl with UVA may safely treat psoriasis without cancer risk.
6 citations
,
September 2024 in “Metabolism and Target Organ Damage” Skin enzymes convert topical drugs into active forms, affecting drug effectiveness and safety.
Tropical herbs have potential for cosmetics but need more research and standardization.
July 2022 in “Journal of Investigative Dermatology” The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.
91 citations
,
April 2011 in “Journal of Ethnopharmacology” Polygonum multiflorum extract helps grow hair by activating certain hair growth signals in mice.
27 citations
,
February 2017 in “Clinical, Cosmetic and Investigational Dermatology” New compounds were found to help increase hair growth and decrease hair loss.
13 citations
,
May 2021 in “FASEB bioAdvances” Plant-based products can improve hair and skin health without harmful side effects.
7 citations
,
April 2009 in “Bioorganic & Medicinal Chemistry Letters” Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.
7 citations
,
April 1996 in “Archives of dermatological research” Topical tacalcitol can treat psoriasis by acting directly on skin cells.
3 citations
,
July 2020 in “Frontiers in Cell and Developmental Biology” Vitexin Compound 1 may help reduce skin aging caused by UVA light.
2 citations
,
January 2021 in “PLANT ARCHIVES” Andrographolide-loaded topical nanocarriers are a safe and effective treatment for psoriasis.
2 citations
,
January 2020 in “International Journal of Cosmetic Science” Niacinamide does not promote hair growth.
March 2024 in “International journal of nanomedicine” Polymeric nanohydrogels show potential for skin drug delivery but have concerns like toxicity and regulatory hurdles.
January 2023 in “Journal of clinical pharmacy and therapeutics” Isoliensinine, a natural compound, prevents stress-related hair greying by blocking a specific receptor on hair cells.
TH07 is a topical combination of finasteride, latanoprost, and minoxidil, and shows promise.
October 2021 in “JAAD Case Reports” Topical glycopyrrolate lotion helped reduce excessive sweating from eating in a diabetic man.
22 citations
,
September 1986 in “Journal of Investigative Dermatology” Low-dose topical alpha-terthienyl may be a safer option for treating skin conditions with light therapy.
3 citations
,
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Curcumin applied to the skin can start hair growth in mice.
November 2023 in “PubMed” Naringenin and its combination with minoxidil significantly improved hair growth in mice.
2 citations
,
January 2022 in “The Application of Clinical Genetics” A young Russian girl with Meier-Gorlin syndrome has two new mutations in the CDC6 gene.