research Topical treatment with the bacterium-derived c-Met agonist InlB321/15 accelerates healing in the abrasion wound mouse model
Applying InlB321/15 to wounds sped up healing in mice.
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research A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice
RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.
research Chitosan microparticles for sustaining the topical delivery of minoxidil sulphate
Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
research Topical ketoconazole: a systematic review of current dermatological applications and future developments
Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.
research Topical Application of Ketoconazole Stimulates Hair Growth in C3H/HeN Mice
Putting ketoconazole on the skin can help mice grow hair.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research The use of biodegradable microneedle patches to increase penetration of topical steroid for prurigo nodularis.
Biodegradable microneedle patches help topical steroids work better for prurigo nodularis.
research Rational Design of a Topical Androgen Receptor Antagonist for the Suppression of Sebum Production with Properties Suitable for Follicular Delivery
A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Physical methods for topical skin drug delivery: concepts and applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats
CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.
research 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production
Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
research Preparation of 4-aryl-2-trifluoromethylbenzonitrile derivatives as androgen receptor antagonists for topical suppression of sebum production
Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.
research Fluridil, a Rationally Designed Topical Agent for Androgenetic Alopecia
Fluridil safely promotes hair growth in men with androgenetic alopecia.
research Successful treatment of resistant alopecia areata with a phototoxic dose of ultraviolet A after topical 8‐methoxypsoralen application
This therapy effectively treats resistant alopecia areata with minimal side effects.
research Therapy experience in alopecia after COVID-19
The treatment with an oral drug and topical lotion is effective and well-tolerated for hair loss after COVID-19.
research CLINICAL CASE OF FOLLICULITIS DECALVANS IN A PREGNANT WOMAN
Topical treatment is recommended for Folliculitis decalvans in pregnant women.
research Clinical applications of antiandrogens
Antiandrogens are effective for conditions like prostate cancer and skin issues, but more research is needed to confirm their benefits and minimize side effects.
research Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production
A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.
research (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production
The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
research Treatments for Androgenetic Alopecia and Alopecia Areata
Minoxidil and finasteride treat hair loss; more research needed for other options.
research Drug discovery for alopecia: gone today, hair tomorrow
Topical drugs and near-infrared light therapy show potential for treating alopecia.
research Alopecia areata: An update
The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.
research Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators
Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.
research Importance of Sebaceous Glands in Cutaneous Penetration of an Antiandrogen: Target Effect of Liposomes
Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
research New topical antiandrogenic formulations can stimulate hair growth in human bald scalp grafted onto mice
Topical treatments can regrow hair on bald scalps.
research Green Synthesis of Silver Nanoparticles Using Grewia optiva Leaf Aqueous Extract and Isolated Compounds as Reducing Agent and Their Biological Activities
Silver nanoparticles made from Grewia optiva leaf extract show strong antibacterial, antioxidant, and hair growth benefits.
research Interventions for morphea
Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
research Thyroid receptor agonists for the treatment of androgenetic alopecia
Thyroid receptor agonists may treat male pattern baldness without harmful side effects.