research A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle
Endoglin is important for proper hair growth cycles and stem cell activation in hair follicles.
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research mTOR signaling in hair follicle and hair diseases: recent progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
research Signaling pathways involved in hair follicle cycling and morphogenesis
Hair growth and development are controlled by complex signaling pathways.
research Canonical and emerging regulatory mechanisms of tissue remodeling: shared principles across organs and therapeutic opportunities
Understanding tissue remodeling can help create precise treatments for various organ issues.
research Roles of H ippo signaling pathway in size control of organ regeneration
The Hippo signaling pathway helps control organ size during regeneration by regulating gene expression.
research Fibroblast bioelectric signaling drives hair growth
Fibroblast bioelectric signaling can promote hair growth and may help treat hair loss.
research Tissue resident and follicular Treg cell differentiation is regulated by CRAC channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Regulatory T cells modulate bone marrow stromal cell osteogenesis by activating ROCK-myosin axis and cell contractility
Regulatory T cells enhance bone formation by influencing cell mechanics.
research 877 Small T antigen from a folliculotropic polyomavirus activates canonical Wnt/β-catenin signaling in vivo
A virus protein can activate a pathway that may lead to abnormal hair follicle development.
research Activation of Wnt Signaling in Hematopoietic Regeneration
Wnt10b helps blood stem cells grow after injury.
research Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.AktWT mice
Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
research A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle
Endoglin is crucial for proper hair growth cycles and stem cell activation in mice.
research Langerin+ Dendritic Cells in Cutaneous Fibrosis: The TGF-β1 Signaling Axis
Targeting specific cell interactions may help treat skin fibrosis.
research Synchronizing actin and microtubules for axonal branching
Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.
research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Mesenchymal-epidermal interactions in hair follicle cycling and regeneration
STAT5 and Sox18 are crucial for hair growth and wound healing.
research Hairy tale of signaling in hair follicle development and cycling
Hair growth and development are controlled by specific signaling pathways.
research Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
Wnt1/βcatenin signaling is crucial for heart repair after injury.
research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction
Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
research Non-canonical Wnt signaling promotes directed migration of intestinal stem cells to sites of injury
Non-canonical Wnt signaling helps intestinal stem cells move to injury sites for tissue repair.
research Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.
research Involvement of the Edar Signaling in the Control of Hair Follicle Involution (Catagen)
Edar signaling is crucial for controlling hair growth and regression.
research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)
A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
research Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration
The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
research Decision letter: Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin
ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.
research Decision letter: Coordinated hedgehog signaling induces new hair follicles in adult skin
Hedgehog signaling can create new hair follicles but may also cause tumors.
research Hair follicle stem cell proliferation, Akt and Wnt signaling activation in TPA-induced hair regeneration
TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
research Parallels in signaling between development and regeneration in ectodermal organs
research Hedgehog-Wnt Interactions during Pathologic Epithelial Bud Development and Skin Tumorigenesis.
Wnt signaling is crucial for Hedgehog-driven skin tumor growth.