45 citations
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January 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
43 citations
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August 2016 in “Scientific Reports” Cinnamomi cortex may help treat prostate enlargement by reducing related proteins.
38 citations
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June 2005 in “Contact Dermatitis” Patient had scalp allergy from minoxidil; test helped identify cause and suggest alternative treatments.
37 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
36 citations
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December 2016 in “Journal of The American Academy of Dermatology” The normal range for the hair pull test is 2 hairs or fewer, and washing or brushing hair before the test does not affect the results.
36 citations
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October 2009 in “Journal of Investigative Dermatology” Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
34 citations
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February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.
33 citations
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September 2017 in “Molecules” Red ginseng oil and its components help promote hair regrowth and could treat hair loss.
33 citations
,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
31 citations
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December 2010 in “International Journal of Andrology” Men with testicular cancer were less likely to experience baldness and severe acne.
30 citations
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June 1988 in “Journal of Steroid Biochemistry” Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.
29 citations
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July 2013 in “The Journal of Sexual Medicine” Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.
27 citations
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February 2017 in “Biomedicine & Pharmacotherapy” White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
25 citations
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November 2015 in “Journal of Ethnopharmacology” Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.
22 citations
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September 2015 in “Fertility and Sterility” The oral glucose tolerance test is effective in detecting abnormal glucose tolerance in Indian women with PCOS.
18 citations
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October 2017 in “Drug Design Development and Therapy” DA-9401 helps protect rat testis from finasteride damage.
17 citations
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March 2020 in “Frontiers in Chemistry” Compounds from the plant Mammea siamensis may help treat hair loss.
16 citations
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August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
15 citations
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July 2019 in “Journal of Biological Inorganic Chemistry” Finasteride helps prevent kidney stones, but side effects need more research.
15 citations
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October 2011 in “Gynecological Endocrinology” Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.
14 citations
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May 2013 in “Experimental Dermatology” The modified wash test is better than TrichoScan® for diagnosing hair loss.
14 citations
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December 1998 in “The Journal of Clinical Endocrinology and Metabolism” MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.
13 citations
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July 2018 in “General and comparative endocrinology” Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.
12 citations
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September 2018 in “Journal of Drug Delivery Science and Technology” The silk fibroin hydrogel with FGF-2-liposome can potentially treat hair loss in mice.
11 citations
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November 1982 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
9 citations
,
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
8 citations
,
November 2015 in “Saudi Journal of Biological Sciences” A mix of Panax ginseng and bee-pollen may help prevent prostate enlargement in rats.
8 citations
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January 2015 in “International journal of trichology” A woman's total hair loss was linked to a Borrelia infection and was reversed with appropriate treatment.
6 citations
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June 2018 in “PLOS ONE” The Alopecia Areata Assessment Tool (ALTO) effectively identifies alopecia areata from other hair loss types but needs more validation.