research Systemic subchronic toxicity and comparison of four selenium nutritional supplements by 90-day oral exposure in Sprague-Dawley rats
High doses of some selenium supplements caused liver and reproductive harm in rats.
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870-900 / 1000+ results research Natural variability and the influence of concurrent control values on the detection and interpretation of low-dose or weak endocrine toxicities.
Control variability makes it hard to confirm low-dose endocrine effects.
research STRUCTURAL-FUNCTIONAL REORGANIZATION OF SKIN AND ITS DERIVATIVES UNDER EXPERIMENTAL SUBACUTE OF INTOXICATION BY HEAVY METALS
Heavy metals can damage skin and hair in mice.
research Поняття міжкультурної комунікації та порівняльна характеристика німецької та української культур (на матеріалі німецької мови)
Low-dose effects in rodent studies are hard to confirm due to confounding factors and control group variability.
research Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.
TCDD reduces EGF receptor activity and causes various developmental changes in animals.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research Toxicity of Chlorinated Aromatic Compounds in Animals and Humans: In Vitro Approaches to Toxic Mechanisms and Risk Assessment
Chlorinated compounds like TCDD can cause skin issues and chloracne by affecting cell behavior.
research Current status of keratinized matrices in Toxicology : Comparison of hair and nails
Nails could be used to check long-term drug use, but more research is needed.
research Some histological and biochemical evaluation on commercial hair dyes
Commercial hair dyes can harm the skin and liver.
research K6/ODC transgenic mice as a sensitive model for carcinogen identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research Metabolite screening of aromatic amine hair dyes usingin vitrohepatic models
The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.
research Preliminary toxicity profile of arotinoids SMR-2 and SMR-6 in male B6D2F1 mice*1
SMR-2 and SMR-6 are much more toxic than retinoic acid, causing severe side effects.
research Toxic Trace Metals and Pathological Changes in Organs of Rats Fed with Extract of Polluted Grasses
Eating plants from polluted areas can cause liver and kidney damage in rats due to toxic metals.
research NTP Toxicology and Carcinogenesis Studies of C.I. Acid Orange 3 (CAS No. 6373-74-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
C.I. Acid Orange 3 caused cancer in female rats but not in male rats or mice.
research Multiple readout assay for hormonal (androgenic and antiandrogenic) and cytotoxic activity of plant and fungal extracts based on differential prostate cancer cell line behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
research Hair
Hair can reveal toxic elements and drugs in the body.
research 8 / Experimental induction of tenuazonic acid toxicity in mice model
Low levels of tenuazonic acid can severely damage vital organs.
research Alopecia and Associated Toxic Agents: A Systematic Review
Thallium, mercury, selenium, and colchicine strongly cause hair loss.
research Chronic toxicity of 3,4,3′,4′-tetrachlorobiphenyl in the marmoset monkey (Callithrix jacchus)
High doses of TCB cause severe health issues in marmoset monkeys.
research Studies of the components of an oral contraceptive agent in albino rats. I. Estrogenic component
High doses of ethynylestradiol in rats caused growth issues, organ changes, and some tumors, but didn't increase overall tumor rates.
research Small Mammal Populations and Community under Conditions of Extremely High Thallium Contamination in the Environment
High thallium contamination severely harms small mammal populations, causing health issues and low population density.
research S2926 Hepatic Steatosis and Acute Liver Injury in Chronic Arsenic Exposure
Chronic arsenic exposure can cause liver damage and other health issues.
research Workplace-related environmental exposure and its potential influence on hair mineral and gut microbiota in cloned working dogs
Environmental conditions can affect toxic mineral levels and gut bacteria in working dogs.
research Internal medicine-important advances in clinical medicine: toxic shock syndrome.
research İNSAN FƏALİYYƏTİ NƏTİCƏSİNDƏ SÜRÜNƏNLƏRİN SÜMÜK VƏ ƏZƏLƏ TOXUMASINDA YÜKSƏK TOKSİKİ TƏSİRLİ MİKROELEMENTLƏRİN TOPLANMASI
Reptiles on the Absheron Peninsula accumulate toxic elements in their tissues but survive due to tissue resilience.
research Topical absorption and systemic toxicity
Some chemicals absorbed through the skin can cause serious health problems.
research A liquid chromatography/tandem mass spectrometry method for determination of aristolochic acid‐I in rat plasma
A reliable method was developed to measure aristolochic acid-I in rat blood.
research Hepatic and renal impairment and degenerative changes caused by carbon black nanoparticles in mice
Carbon black nanoparticles can harm liver and kidney function in mice.
research The human gut chemical landscape predicts microbe-mediated biotransformation of foods and drugs
The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.
research Anticancer drugs in surface waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.