research Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
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180-210 / 1000+ results research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research Preventive effects of cedrol against alopecia in cyclophosphamide-treated mice
Cedrol may prevent hair loss caused by chemotherapy better than minoxidil.
research INHALATION TOXICITY STUDIES OF AQUEOUS DISPERSION RESIN
Aqueous dispersion resin is safe to inhale at levels below 30 mg/m³.
research Alpinia zerumbet an essential medicinal herb
Alpinia zerumbet is a promising medicinal herb with various health benefits.
research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research Low‐dose in utero exposure to finasteride promotes developmental changes in both male and female gerbil prostates
Exposure to low doses of finasteride in the womb causes changes in the prostate of both male and female gerbils.
research Cyproterone Acetate: A Genotoxic Carcinogen?
Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
research Maternal coffee consumption during pregnancy and pubertal development in children: A cohort study
High coffee intake during pregnancy may cause earlier puberty in daughters.
research Selenium poisoning from consumption of contaminated wheat: a case series from rural Maharashtra, India
Contaminated wheat caused hair loss and other symptoms due to high selenium, but washing it with alkaline water helped.
research Protective role of hesperidin in finasteride-induced testicular toxicity in adult male Wistar rats: Insights into oxidative stress, apoptosis, and ultrastructure of seminiferous tubules
Hesperidin helps protect against testicular damage caused by finasteride.
research Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria
Mozuku seaweed fucoidan can inhibit harmful skin bacteria growth.
research Gene and tonic: Sonic hedgehog disruption and fetal alcohol syndrome
research Unexpected refractory hypotension following intradermal minoxidil injection
research Minoxidil overdose with hypotension effectively managed with norepinephrine, rather than dopamine
research Evaluating the Role of lncRNAs in the Incidence of Cardiovascular Diseases in Androgenetic Alopecia Patients
research Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Incorporation of Isotopically Labeled Cocaine and Metabolites into Human Hair: 1. Dose-Response Relationships
Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.
research Cutaneous and Ocular Late Complications of Sulfur Mustard in Iranian Veterans
Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.
research Long-term toxicity studies on oxidation hair dyes
The hair dye formulations tested did not cause long-term toxicity or cancer in mice.
research Hair growth promoting effect of Zizyphus jujuba essential oil
Zizyphus jujuba essential oil can promote hair growth.
research Glibenclamide inhibits cell growth by inducing G0/G1 arrest in the human breast cancer cell line MDA-MB-231
Glibenclamide slows breast cancer cell growth by stopping cell division.
research Amphetamine and N-Acetylamphetamine Incorporation into Hair: An Investigation of the Potential Role of Drug Basicity in Hair Color Bias*
Basic drugs like amphetamine are absorbed more in darker hair than lighter hair.
research Interspecies variations in response to topical application of selected zinc compounds
Different zinc compounds cause varying levels of skin irritation in animals.
research Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism?
Human enzymes can detoxify harmful substances but might also increase their cancer risk.
research Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia
Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.
research The Occurrence and Incorporation of Copper and Zinc in Hair and their Potential Role as Bioindicators: A Review
Copper and zinc in hair can indicate health conditions.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research An Animal Model of Trichloroethylene-Induced Skin Sensitization in BALB/c Mice
Trichloroethylene causes skin inflammation in mice by increasing certain immune proteins.
research Acute selenium poisoning by paradise nuts (Lecythis ollaria)
Eating paradise nuts led to selenium poisoning, causing nausea, hair loss, and other symptoms in two women.