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EGFR and MEK inhibitors reduce PD-L1 in hair follicles, possibly causing inflammation.

A patient with a rare disease had a unique genetic mutation linked to their symptoms.

A specific gene variant (rs4833095) is linked to a higher risk of alopecia areata in Koreans.

Researchers found a new genetic mutation causing a rare hair loss condition in the first Japanese child studied.

Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

CD34 is crucial for skin tumor development in mice.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Lipid-antigen stimulation may play a role in folliculotropic mycosis fungoides.

Faulty LEF1 activation causes faster skin cell differentiation in premature aging syndrome.

Inhibiting the PI3K/Akt pathway may help prevent radiation-induced liver injury.

Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.

S100A3 protein is crucial for hair shaft formation in mice.

Increased PHGDH expression causes early melanin buildup in hair follicles.

Blocking certain proteins in mouse skin can reduce and shrink skin tumors.

Hair root analysis can effectively detect somatic mosaicism in double cortex syndrome.

Targeting PTEN can improve healing in venous leg ulcers.

A patient with a new PLEC gene mutation showed symptoms of both muscular dystrophy and myasthenia gravis, which improved with steroid treatment.

The Thr1022Ala variant in the hairless gene is not a disease-causing mutation.

Different keratins have unique expression patterns in mouse skin cells.

A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.

High levels of ornithine decarboxylase can cause tumors in mouse skin.

Increased EGFR gene variations may predict chemotherapy outcomes in small cell lung cancer patients.

An automated system can predict death risk in thin melanoma by analyzing immune cells.

A gene mutation causes woolly hair in a Syrian patient.

Mutations in the LSS gene cause hair loss and may affect brain development, with varying severity.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.