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Three molecular subtypes of advanced skin T-cell lymphoma were identified, with potential biomarkers for predicting treatment response and disease progression.

TB lymphadenitis can occur in people with weakened immune systems, like those with SLE.

Trichoscopy is a quick, accurate, and non-invasive method to diagnose and treat non-scarring hair loss.

Increasing Treg cells in the skin does not cure hair loss from alopecia areata in mice.

Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.

Some hair proteins are specific to hair, while others are also found in skin cells.

Certain blood markers, especially MLR, can help diagnose alopecia areata.

A heterozygous mutation in HTRA1 can cause severe CARASIL symptoms.

Monilethrix is a genetic disorder causing brittle hair, diagnosed using tricoscopy.

Targeted protein degraders show promise in treating cancer but need to target more diverse proteins.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

Trichoscopy helps tell apart alopecia areata and trichotillomania in Asians by looking at specific hair and scalp features.

Alopecia areata may be linked to higher heart disease risk.

Hair changes and a high occipital hairline may help diagnose Trichorhinophalangeal Syndrome.

Trichothiodystrophy involves brittle hair due to low sulfur amino acids, not a transport defect.

Trichorrhexis nodosa is mainly caused by hair trauma and improves with gentler hair care.

JAK inhibitors may help treat alopecia areata by reversing hair loss.

Expanding CD4+ Tregs can stop hair loss in alopecia areata.

The role of γδT-cells in causing alopecia areata remains unclear.

Protein microarrays are highly sensitive tools useful for disease diagnosis and studying proteins.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

CD28 is a promising target for treating alopecia areata with belatacept.

CD28 is a promising target for treating alopecia areata with belatacept.

Trichoscopy effectively diagnoses and assesses hair loss severity in androgenetic alopecia and alopecia areata.

Trichoscopic patterns often overlap in scalp disorders, so dermatologists need to stay updated.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.