5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.
November 2011 in “Nature Clinical Practice Urology” 5ARIs effectively treat and manage BPH by reducing prostate size and symptoms.
March 2005 in “European Urology Supplements” 3 citations
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December 2016 in “Der Urologe” Dutasteride reduces prostate cancer risk by 23% in high-risk men.
April 2018 in “The Journal of Urology” Phosphodiesterase inhibitors like tadalafil can reduce cell growth in BPH caused by CD8+ T cells in low androgen conditions.
March 2023 in “The Journal of Urology” Men with better urinary symptoms have a lower risk of death.
January 2014 in “Hebei yixue” Combining tamsulosin and finasteride effectively improves urinary symptoms in elderly BPH patients.
August 2002 in “Inpharma Weekly” November 2013 in “The Journal of Urology” 4 citations
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February 2016 in “The Journal of urology/The journal of urology” Most care for benign prostatic hyperplasia follows guidelines, but 5-α reductase inhibitors are often used incorrectly.
5 citations
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June 2015 in “Chinese journal of natural medicines/Zhongguo tianran yaowu/Chinese Journal of Natural Medicines” Tripterygium wilfordii multiglycoside effectively reduced prostate enlargement in rats without harmful effects.
82 citations
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February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.
2 citations
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April 2021 in “Canadian Journal of Urology” Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
December 2004 in “Annales d Urologie” Finasteride may reduce prostate cancer risk.
November 2003 in “PubMed”
August 2024 in “Journal of Renal Injury Prevention” A new method using a Foley catheter on a ureteroscope makes difficult urethral catheterization easier and more effective.
1 citations
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October 2013 in “Urology” More men are using medication for benign prostatic hyperplasia, influenced by marketing and FDA approvals.
September 2009 in “European Urology Supplements” After prostate removal surgery, higher initial prostate size was linked to higher urethral PSA levels and more severe male pattern baldness.
August 2003 in “Oncology Times” The trial on testosterone replacement therapy in older men faced concerns due to prostate cancer risk.
January 2025 in “Investigative and Clinical Urology” SHPro® improved urinary symptoms and erectile function in men and is safe.
December 2013 in “Urology reports (St - Petersburg)” Sonirid Duo effectively treats benign prostatic hyperplasia.
184 citations
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January 2000 in “European Urology” Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
38 citations
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January 2005 in “PubMed” Dutasteride effectively treats enlarged prostate with manageable side effects.
19 citations
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October 2018 in “PLOS ONE” 5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.
3 citations
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January 2019 in “Therapeutic advances in urology” WS PRO 160 I 120 mg effectively treats urinary symptoms from BPH with good safety and tolerability.
4 citations
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April 2015 in “대한비뇨기종양학회지” For better medication adherence in benign prostatic hyperplasia treatment, tamsulosin and finasteride should be packaged together and taken at the same time.
January 2008 in “Journal of Beijing Normal University” Terazosin hydrochloride helps with BPH and blood pressure, but not more than the control.
33 citations
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July 2009 in “Therapeutics and Clinical Risk Management” Finasteride effectively reduces prostate size and lowers surgery risk in men with benign prostatic hyperplasia.
Tamsulosin and finasteride together effectively slow down and prevent BPH progression.