13 citations
,
October 2017 in “Bioscience, Biotechnology, and Biochemistry” Centella asiatica extract may help promote hair growth by blocking a specific cell signaling pathway.
12 citations
,
November 2020 in “Molecules” Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.
12 citations
,
June 2017 in “Cell Cycle” Minoxidil foam helps hair growth by increasing good proteins and decreasing bad pathways in men with hair loss.
11 citations
,
July 2021 in “Physiologia Plantarum” SIPHL1 from tomato enhances plants' response to low phosphate levels.
11 citations
,
January 2018 in “Royal Society Open Science” Scientists found genes linked to the growth of high-quality brush hair in Chinese Haimen goats.
10 citations
,
June 2024 in “American Journal of Clinical Dermatology” Hedgehog pathway inhibitors for advanced basal cell carcinoma can cause side effects, but managing them helps maintain treatment.
8 citations
,
May 2018 in “The Journal of Allergy and Clinical Immunology” Activating the Nrf2 pathway reduces inflammation and cell activation in human hair follicles, suggesting a potential treatment for certain hair loss conditions.
5 citations
,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
4 citations
,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
4 citations
,
May 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” ELL is crucial for gene transcription related to skin cell growth.
March 2026 in “Dermatology and Therapy” Distinct miRNA signatures could help diagnose and treat severe Alopecia Areata.
October 2025 in “Journal of Translational Medicine” Combining biomaterials and cell pathways can improve hair follicle regeneration.
January 2025 in “Fitoterapia” Signaling pathways are key targets for developing effective drugs.
July 2024 in “Frontiers in Pharmacology” Pilose antler extracts help hair growth by activating hair follicle stem cells.
November 2023 in “Frontiers in cell and developmental biology” Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
61 citations
,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
27 citations
,
May 2017 in “Marine Drugs” Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.
3 citations
,
September 2022 in “Frontiers in veterinary science” Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.
1 citations
,
December 2024 in “Scientific Data” Researchers identified key molecular changes in goat hair follicles that could improve cashmere production.
5 citations
,
September 2018 in “Acta histochemica” The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.
194 citations
,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
165 citations
,
September 2001 in “Genes & development” CDP is crucial for lung and hair follicle cell development.
112 citations
,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
72 citations
,
January 2003 in “American Journal of Pathology” A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
57 citations
,
January 2013 in “International Journal of Medical Sciences” Lef1 helps stem cells become hair cells by interacting with specific signaling pathways.
55 citations
,
October 2019 in “Dermatology and therapy” Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.
45 citations
,
April 2016 in “Journal of Dermatological Science” The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
45 citations
,
April 2013 in “Cell Transplantation” Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.
43 citations
,
September 2017 in “Lasers in Surgery and Medicine” LED light therapy may help hair growth by activating certain cell pathways.
43 citations
,
September 2014 in “Molecular Plant” CLE40 and CRN/CLV2 pathways have opposite effects on root growth in Arabidopsis.