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Estradiol gel can cause hair loss in dogs.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Finasteride delivery through skin improved using invasomes and iontophoresis.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Testosterone creams and gels can be effective but have serious risks and should be used only with medical supervision.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Oral testosterone therapy raises heart risk more than other methods.

The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.

Natural permeation enhancers help emulgels deliver drugs through the skin more effectively.

Menthol-based microemulsions improve skin delivery of finasteride and silodosin.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.