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Cyproterone acetate with estradiol improved women's self-confidence and emotional well-being without a difference between oral or transdermal methods, but younger women preferred the oral method.

Estradiol gel can cause hair loss in dogs.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

The patient was satisfied with hormone therapy, and her epilepsy remained stable.

A castrated dog developed hair loss and prostate issues from long-term exposure to estrogen cream.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

Hormone therapy for trans individuals is effective and generally safe in the short term.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Estrogen alone can lower testosterone in some transfeminine people.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

The eucalyptus oil system improved skin delivery of hormones, but safety concerns remain.

Dogs exposed to their owners' hormone therapy developed hair loss, but symptoms resolved after stopping the therapy.

Estrogen alone may effectively suppress testosterone in some transfeminine individuals.

Estrogen deficiency can reduce the enzyme activity needed to activate vitamin D.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

3D-printed microneedles improve drug delivery by being precise, cost-effective, and less invasive.

50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.

Transdermal drug delivery systems are effective and promising for future use.

Finasteride delivery through skin improved using invasomes and iontophoresis.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Menthol-based microemulsions improve skin delivery of finasteride and silodosin.

Dissolving microneedles offer efficient, minimally invasive drug delivery through the skin.