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Genetic differences affect breast cancer treatment success with tamoxifen in South African patients.

Lack of TG2 increases fat storage and lowers cell cleanup in skin oil cells.

Glioblastoma cells can make androgens, which might help the tumor grow.

Human TMEM2 does not break down hyaluronan but helps control its metabolism.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Valproic acid does not change biotinidase enzyme activity in children's blood.

TG5 helps maintain hair follicle health, while TG3 aids in hair shaft development.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

TGM3 is important for skin and hair structure and may help diagnose cancer.

The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.

H1 increases risk for neurodegenerative diseases, while H2 offers protection but is linked to other disorders.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

A new enzyme in rats may help regulate hair growth.

Smart nano-PROTACs improve cancer treatment by targeting proteins more precisely and reducing side effects.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Amotosalen-treated donor T-cells can prevent late CMV infection after bone marrow transplants.

Altering SSAT affects fat metabolism and body fat in mice.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

A new mutation in the mitochondrial DNA was found in a boy with MELAS, even though his family didn't show typical signs.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Sulfotransferase in hair follicles helps predict how well minoxidil works for female hair loss.

Transfersomes are better than liposomes for targeting hair follicles in alopecia treatment.

The report expanded knowledge of MBTPS1-related disorders by identifying new symptoms.

The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.

Dopaminergic neurons in the gut have distinct subtypes, some releasing both dopamine and acetylcholine.