research Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations
Transcutol® helps drugs penetrate the skin more effectively in various formulations.
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150-180 / 1000+ results research Over-expression of TSPO in the hippocampal CA1 area alleviates cognitive dysfunction caused by lipopolysaccharide in mice
Increasing TSPO in the brain may help improve memory problems.
research Leflunomide for the treatment of trichodysplasia spinulosa in a liver transplant recipient
Leflunomide successfully treated a rare skin condition in a liver transplant patient.
research Correction of ornithine transcarbamylase (OTC) deficiency in spf‐ash mice by introduction of rat OTC gene
Introducing the rat OTC gene partially corrected OTC deficiency in mice.
research Therapeutic effect of exosomes derived from hepatocyte-growth-factor-overexpressing adipose mesenchymal stem cells on liver injury
Exosomes from modified stem cells may help treat liver injury.
research Proteasome Inhibitors: An Expanding Army Attacking a Unique Target
Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
research Transplantation immunology: Solid organ and bone marrow
Transplant success has improved with better immunosuppressive drugs and donor matching.
research PROTACs: A novel strategy for cancer drug discovery and development
PROTAC technology shows promise for cancer treatment but needs more effective E3 ligase recruiters.
research Dermal drug delivery with ethosomes: therapeutic potential
Ethosomes can effectively deliver drugs deep into the skin, improving treatment for various skin conditions.
research Characterization of Recombinant Human Liver Thermolabile Phenol Sulfotransferase with Minoxidil as the Substrate
Both enzyme forms can sulfate minoxidil.
research Enhancement of percutaneous absorption of Finasteride by cosolvents, cosurfactant and surfactants
Transcutol P best increases Finasteride absorption for hair loss treatment.
research Molecular Interactions and Release Mechanisms of Finasteride in β-CD and Trimethyl-β-CD Complexes: A Computational and Experimental Approach
TM-β-CD improves finasteride's solubility and delivery, while β-CD offers better long-term release.
research Ethosomes in hair dye products as carriers of the major compounds of black tea extracts
Ethosomes improve black tea extract absorption in hair dye.
research Evaluation of Serum Ferritin, Creatinine and Liver Enzymes in Patients with ß- thalassemia After Administration of Deferasirox
Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.
research Vertebral epidermal transamidases
Transamidases are present in the epidermis but their exact role is unclear.
research Epidermal and hair follicle transglutaminases and crosslinking in skin
research Exploring the Therapeutic Potential of TGF-β Inhibitors for Liver Fibrosis: Targeting Multiple Signaling Pathways
TGF-β inhibitors may help treat liver fibrosis by targeting various pathways.
research The silver locus product (Silv/gp100/Pmel17) as a new tool for the analysis of melanosome transfer in human melanocyte–keratinocyte co‐culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research Transdermal delivery of finasteride invasomes using taguchi robust design method
Invasomes with 0.5% limonene greatly improve skin delivery of finasteride.
research Solubilizing steroidal drugs by β-cyclodextrin derivatives
Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
research Purification and characterization of rat liver minoxidil sulphotransferase
Enzyme purified and characterized for minoxidil sulphation in rat liver.
research Very-long-chain Acyl-CoA Synthetases
Very-long-chain acyl-CoA synthetases and fatty acid transport proteins play key roles in fatty acid metabolism and lipid processing in different tissues.
research Human epidermal transglutaminase. Preparation and properties.
The enzyme from human skin can cross-link proteins and needs calcium to work.
research Harnessing Milk-derived Extracellular Vesicles for Oral Drug Delivery and Therapeutic Application
research Characterization of the Role of Transferrin receptor 1 (Tfr1) in the Intestinal Epithelium, Pancreas, and Skin
Transferrin receptor 1 is essential for normal function in the intestines, pancreas, and skin.
research A NEW GENERATION OF MARKERS FOR CANCER DETECTION AND DRUG TRANSPORT
New markers can detect tumors, aid drug delivery, and treat cancer effectively and safely.
research Microencapsulated cell tracking
Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
research Transfer of peanut allergy from donor to recipient after liver transplant
Peanut allergies can be transferred through organ transplants.
research Cytoprotective effects of paeoniflorin are associated with translocator protein 18 kDa
Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.
research INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Human serum albumin nanoparticles for enhanced drug delivery to treat breast cancer: Preparation and In Vitro assessment
HSA nanoparticles can improve tamoxifen delivery for breast cancer treatment, reducing side effects.