10 citations
,
August 2015 in “Journal of biophotonics” Hair follicles help substances penetrate the skin faster and more effectively.
January 2020 in “Der Pharmacia Lettre” Nanoparticle-based herbal remedies could be promising for treating hair loss with fewer side effects and lower cost, but more research is needed.
96 citations
,
April 2017 in “Oncotarget” Smaller nanoemulsions can penetrate skin and hair follicles better, which may be useful for delivering drugs and vaccines through the skin.
39 citations
,
April 2012 in “Journal of controlled release” New method uses hair follicles to deliver drugs deep into the skin.
122 citations
,
April 2011 in “European Journal of Pharmaceutics and Biopharmaceutics” Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.
60 citations
,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
54 citations
,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
52 citations
,
January 2020 in “Scientific Reports” NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” Lipid-polymer hybrid nanoparticles show promise for skin treatments but need better formulation strategies.
156 citations
,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
97 citations
,
September 2011 in “British Journal of Dermatology” The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
42 citations
,
July 2015 in “Cosmetics” Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.
1 citations
,
December 2022 in “Pharmaceutics” Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.
July 2023 in “Journal of Cosmetic Dermatology” Ethosomes could improve how well skin treatments work, but more research is needed on their safety and stability.
2 citations
,
January 2018 in “Elsevier eBooks” Lipid nanoparticles improve drug delivery through the skin, offering stability, controlled release, and better compatibility with skin.
33 citations
,
June 2007 in “International Journal of Pharmaceutics” The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.
16 citations
,
November 2020 in “International journal of pharmaceutics” Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
13 citations
,
September 2020 in “Sensors” Hair follicles have a pH gradient, increasing towards the root.
110 citations
,
January 2014 in “Journal of Controlled Release” Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.
14 citations
,
August 2021 in “Journal of Pharmaceutical Sciences” Cholesterol- and phospholipid-free niosomes improve deep skin drug delivery.
11 citations
,
April 2025 in “Pharmaceutics” New treatments like plant extracts, nanocarriers, and 3D bioprinting show promise for hair loss, but more research is needed.
May 2025 in “International Journal of Applied Pharmaceutics” Nanocarriers could improve hair loss treatments by delivering drugs directly to hair follicles.
38 citations
,
March 2015 in “Journal of controlled release” IMSG nanoparticles improve vaccine delivery and immune response through hair follicles.
29 citations
,
May 2007 in “International journal of pharmaceutics” Different compounds move through artificial sebum at different rates, which can help choose the best ones for targeting hair follicles.
19 citations
,
July 2020 in “Journal of drug delivery science and technology” Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
6 citations
,
January 2025 in “Molecules” Combining polymers and lipids may improve antioxidant delivery for wound healing, but practical challenges remain.
6 citations
,
December 2015 in “International journal of nanomedicine” Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
14 citations
,
November 2019 in “Materials” Diamond nanoparticles can penetrate skin and reach hair follicles, useful for imaging applications.
June 2025 in “Journal of Cluster Science” Metal nanoparticles show promise for treating hair loss but need more research to ensure safety.
49 citations
,
September 2008 in “International journal of pharmaceutics” Artificial sebum L closely mimics human sebum for drug delivery research.