October 2025 in “Journal of the Endocrine Society” The patient was satisfied with hormone therapy, and her epilepsy remained stable.
June 2025 in “Journal of the American Academy of Dermatology”
October 2024 in “Journal of the Endocrine Society” Feminizing hormone therapy increases kidney filtration rate.
October 2022 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.
April 2020 in “Journal of the Endocrine Society” Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
7 citations
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May 2010 in “Drug Delivery” Retinoic acid and DMSO improve gene delivery to mouse skin for potential hair and skin disease treatment.
Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.
153 citations
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April 1998 in “Current Biology” The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
43 citations
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February 1999 in “Biochemical Journal” Overexpression of SSAT in mice causes hair loss, liver damage, and sensitivity to polyamine analogues.
13 citations
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March 1999 in “Biochemical Journal” Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
157 citations
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May 2016 in “Plastic and reconstructive surgery/PSEF CD journals” Facial feminization surgery is safe and patients are satisfied, but more detailed research is needed.
131 citations
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September 2010 in “The Laryngoscope” Forehead modification greatly increases the perception of femininity and is a safe procedure.
January 2024 in “JMIR Dermatology” Few dermatology programs mention gender-affirming care, highlighting a need for better training and visibility.
January 2024 in “Surgical & Cosmetic Dermatology” Hair transplants can help transgender individuals match their appearance with their gender identity.
28 citations
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July 2008 in “Developmental Biology” Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
6 citations
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January 2014 in “Genetics and Molecular Research” The method successfully created stable transfection donor cells for goat hair follicle research.
1 citations
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July 2006 in “Journal of Investigative Dermatology” A 4kb fragment of the desmocollin 3 promoter targets gene expression to specific skin and hair follicle areas.
April 2019 in “Journal of Investigative Dermatology” Researchers created a new mouse model for studying scleroderma.
74 citations
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June 2018 in “Cell death and disease” Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.
19 citations
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May 2001 in “Endocrinology” Mrp3 may aid in wound healing and hair growth.
184 citations
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September 2006 in “PLoS Genetics” The Apc gene is crucial for normal skin and thymus development.
144 citations
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December 2004 in “Molecular Endocrinology” The vitamin D receptor is essential for normal hair growth, even without its usual binding.
88 citations
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August 1998 in “Carcinogenesis” High levels of ODC and a mutant Ha-ras gene cause tumors in mice.
43 citations
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April 2010 in “Developmental Biology” Sebaceous glands can form new hair follicles when activated, but hair follicle bulges cannot.
108 citations
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February 2013 in “JAMA” Transgender treatment includes hormones and surgery, but long-term effects are unknown and counseling is needed.
13 citations
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March 2023 in “Cureus” Transgender individuals face insurance barriers to gender-affirming surgery, needing policy reforms for better access.
10 citations
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August 2022 in “Journal of clinical sleep medicine” Transgender youth have more sleep disorders, but gender-affirming therapy may help reduce them.
February 2026 in “eYLS (Yale Law School)” Denying transgender minors gender-affirming care, while allowing it for cisgender minors, is sex discrimination.
75 citations
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March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
October 2025 in “Contribuciones a las Ciencias Sociales” Alopecia in transgender individuals on hormone therapy can worsen emotional distress and affect self-esteem.