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Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Younger transgender women have surgery earlier, are mostly attracted to men, and show more preoperative depression that improves after surgery compared to older transgender women.

Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.

Transgender men on testosterone therapy need ongoing gynecologic care due to potential cancer risks.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Forehead reduction and orbital contouring are important for satisfactory facial feminization in transgender females, with high satisfaction and low long-term problems.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Finasteride effectively treats hair loss in transgender men with few side effects.

Facial contouring is crucial for the satisfaction and well-being of Chinese transgender females.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

Facial feminization surgery is safe and patients are satisfied, but more detailed research is needed.

A hair transplant using hair from the back of the head and pubic area was successful in creating a feminine hairline for a male-to-female transgender person.

Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.

Hair transplants are effective for some women and many male-to-female transgender patients if done carefully by an experienced team.

Testosterone treatment in transgender teens can worsen acne, requiring careful treatment due to mental health and medication side effects.

Uterine transplants for transgender women are feasible but need more research.

Transgender individuals can maintain stable kidney function post-transplant with gender-affirming care, but need careful management of hormone therapy risks and regular health screenings.

Transgender patients use hair restoration surgery to match their hairline with their gender identity.

Doctors are preparing to potentially perform uterus transplants in transgender women, considering technical, hormonal, and ethical factors.

Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.

Genetics may play a significant role in gender dysphoria.

This special edition focuses on the unique aspects of treating skin conditions in women, including during pregnancy and in diverse populations like women of color and transgender patients.