research Estrogen modulates mesenchymal-epidermal interactions in the adult nipple
Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.
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research Activin Controls Skin Morphogenesis and Wound Repair Predominantly via Stromal Cells and in a Concentration-Dependent Manner via Keratinocytes
Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.
research Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
research Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
research Biology of the wool follicle: an excursion into a unique tissue interaction system waiting to be re‐discovered
The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
research A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice
A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.
research The E6/E7 oncogenes of human papilloma virus and estradiol regulate hedgehog signaling activity in a murine model of cervical cancer
HPV genes and estradiol increase a cancer-related signaling pathway, which may be targeted for cervical cancer treatment.
research Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure
Lack of certain cells causes abnormal nipple development and nursing failure.
research PRC 2 preserves intestinal progenitors and restricts secretory lineage commitment
PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.
research Plasticity and Cytokinetic Dynamics of the Hair Follicle Mesenchyme: Implications for Hair Growth Control
Hair growth is influenced by dynamic changes in hair follicle cells, which could help treat hair loss.
research Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
research Understanding the role of sex hormones in cancer for the transgender community
Hormone therapy affects cancer risks in transgender individuals differently than in cisgender people, and more research is needed to understand these risks and improve cancer screening guidelines.
research 319 Acne, androgenetic alopecia, and atopic dermatitis in transgender patients on hormone therapy: A retrospective comparative cohort study
Transgender patients on hormone therapy experience more acne and hair loss, but less skin inflammation.
research Incidence and Factors Associated With Androgenetic Alopecia Among Transgender and Gender-Diverse Patients Treated With Masculinizing Hormone Therapy
Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.
research A Retrospective Cohort Study of Transgender Adolescents' Gender-Affirming Hormone Discontinuation
Most transgender adolescents continued hormone treatment, with few stopping due to reasons other than returning to their birth gender.
research Scalp Hair Regrowth in Hormone-Treated Transgender Woman
Hormone therapy with estradiol and spironolactone can regrow scalp hair in transgender women by lowering testosterone to female levels.
research 53039 The prevalence of androgenetic alopecia with hormone therapy in transgender men: a systematic review and single-arm meta-analysis
Many transgender men on testosterone therapy experience hair loss.
research Prevalence of Psoriasis and Perceived Association with Hormone Therapy in Transgender Adults
Psoriasis rates in transgender people are similar to the general population, but hormone therapy might affect it.
research Efficacy of topical minoxidil in enhancing beard growth in a group of transgender assigned female at birth individuals on gender affirming hormone therapy
Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.
research Gender-Affirming Hormone Therapy Among Transgender and Gender Diverse Patients Receiving Laser Hair Removal Prior to Gender-Affirming Surgery
Most transgender patients getting laser hair removal before gender-affirming surgery are already on hormone therapy, which might affect the hair removal process.
research Gender‐affirming hormone therapy for transgender and gender‐diverse adults in Australia
Gender-affirming hormone therapy improves mental health and gender incongruence but requires careful management of cardiovascular and cancer risks.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Insights Into the Cardiomodulatory Effects of Sex Hormones: Implications in Transgender Care
Gender-affirming hormone therapy may increase heart disease risk in transgender individuals.
research 8483 Changes in kidney hemodynamics during gender-affirming hormone therapy in transgender individuals - findings from the KNIGHT pilot study
Feminizing hormone therapy increases kidney filtration rate.
research A Review of Gender-Affirming Hormone Therapy for Transgender and Gender Diverse Adults in South Korea
Gender-affirming hormone therapy in South Korea aligns with international guidelines and has specific side effects.
research Scalp hair parameter changes in transgender individuals commencing gender-affirming hormone therapy: A 24-week prospective observational study
This study observed scalp hair parameter changes in transgender individuals over 24 weeks of gender-affirming hormone therapy. It found that masculinizing hormone therapy (MHT) with testosterone can lead to androgenetic alopecia (AGA), while feminizing hormone therapy (FHT) with estradiol and antiandrogens can improve hirsutism. The study highlights the role of sex steroids in influencing hair growth by affecting the hair cycle, with androgens shortening the anagen and telogen phases, and estrogens potentially prolonging anagen and inhibiting catagen.
research SAT645 Cardiac Autonomic Modulation In Transgender Men Under Gender-affirming Hormone Therapy
Testosterone treatment may affect heart response to stress in transgender men.
research HIV pre-exposure prophylaxis in transgender women: a subgroup analysis of the iPrEx trial
PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.
research Hair loss among transgender and gender‐nonbinary patients: a cross‐sectional study
Transgender and nonbinary individuals experience hair loss, with transmen on testosterone seeing more severe hair loss, while feminizing hormones may stabilize hair loss in transwomen.