131 citations
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September 2010 in “The Laryngoscope” Forehead modification greatly increases the perception of femininity and is a safe procedure.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
January 2024 in “JEADV clinical practice” Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
1 citations
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April 2024 in “Archives of disease in childhood” Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.
June 2023 in “Sri Lanka Journal of Menopause”
October 2023 in “Journal of the Endocrine Society” Hormonal therapy in adults with gender dysphoria often leads to skin issues like acne, requiring a team of skin and hormone doctors.
2 citations
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January 2020 in “Elsevier eBooks” The document concludes that individualized Facial Feminization Surgery plans and comprehensive care are crucial for successful outcomes.
December 2022 in “Brazilian Journal of Health Review” Patients with Complete Androgen Insensitivity Syndrome need psychological support and multidisciplinary care for complex treatment decisions.
January 2025 in “Journal of Men s Health” Young men's erectile dysfunction is linked to mental health issues and risky behaviors promoted by online communities, highlighting the need for better mental health support and healthy masculinity standards.
January 2024 in “Medicina” Proper planning and technique in upper-face feminization surgery are crucial to avoid complications and revisions.
June 2025 in “Journal of the American Academy of Dermatology”
July 2011 in “British Journal of Dermatology” Hormone treatment caused hair loss, finasteride helped regrowth.
23 citations
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October 2015 in “Andrology” New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
Menopause is a clear hormonal transition in women, while men experience a gradual testosterone decline, with some needing lifestyle changes and targeted therapy.
10 citations
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February 2019 in “Toxicological Sciences” Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.
54 citations
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April 2010 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
10 citations
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May 2009 in “Cases Journal” A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.
37 citations
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February 2013 in “Maturitas” Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
January 2025 in “HORMONES” Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.
March 2026 in “Journal of Dermatological Treatment” Topical 3% minoxidil effectively and safely enhances facial hair in transgender men.
December 2023 in “International Journal of Dermatology” Adults with gender dysphoria on hormone treatment often have skin problems like acne, which are common but not always recognized.
January 2021 in “Case Reports” A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.
1 citations
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April 2022 in “Indian Journal of Plastic Surgery” Hormone therapy greatly improves the quality of life for adults seeking gender reaffirmation, but more research is needed in India.
February 2022 in “The Nurse Practitioner” The document aimed to improve healthcare providers' understanding of hormone therapy for transgender and nonbinary patients.
1 citations
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April 2024 in “Journal of Plastic Reconstructive & Aesthetic Surgery”
April 2024 in “Journal of endocrinological investigation” Topical minoxidil helps transgender individuals assigned female at birth grow more facial hair.
36 citations
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May 2017 in “The journal of sexual medicine” Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.
March 2026 in “Anais Brasileiros de Dermatologia” Facial aesthetic procedures improve quality of life for transgender individuals.
2 citations
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March 2025 in “Lynchburg Journal of Medical Science” Testosterone is important for women's health, but more research is needed to guide its use.