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Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.

Apoptotic cells help cause hair follicle cell death during regression.

Understanding snoRNA regulation may help slow skin aging.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Drug repositioning offers hope for new, affordable treatments for a genetic skin disorder called ARCI.

The RNA AL136131.3 slows down hair growth and speeds up hair loss by affecting sugar breakdown in hair follicles.

PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.

Neurosteroids may help treat disorders with too much dopamine activity.

Compound 15a was effective in inhibiting 5α-reductase.

Thyrotropin-Releasing Hormone helps heal wounds in frog and human skin.

Gene expression affects fur development in rex rabbits.

Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.

Expanding CD4+ Tregs can stop hair loss in alopecia areata.

The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.

Choose treatments for sex offenders based on individual needs, using hormonal and nonhormonal options to reduce sexual drive.

Surgical deactivation can significantly reduce or eliminate migraine symptoms.

The androgen receptor gene doesn't affect women with recurrent spontaneous abortions, but having a mutant genotype might protect against it.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Treg cells help repair and regenerate tissues by interacting with local cells.

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.