66 citations
,
March 1998 in “Mayo Clinic Proceedings” Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.
23 citations
,
July 2015 in “The Journal of Membrane Biology” Testosterone increases certain proteins in the uterus, reducing fluid volume.
November 2017 in “Reactions Weekly” Testosterone undecanoate caused hair loss; finasteride improved it but caused stomach issues for one patient.
October 2023 in “IJEM case reports” A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.
A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
24 citations
,
January 2011 in “Sexual Development” Intersex frogs have different brain gene activity related to sex and thyroid hormones.
13 citations
,
May 2019 in “Archives of dermatological research” Tranexamic acid reduces skin aging more in female mice.
January 2025 in “AAPS PharmSciTech” Transethosomes improve drug delivery through the skin and show promise for treating various conditions.
18 citations
,
June 1995 in “International Journal of Dermatology” Women experience various skin issues at different life stages, requiring careful treatment and awareness.
20 citations
,
October 2017 in “Clinical Endocrinology” The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
October 2022 in “Miscellaneous” A rare, non-cancerous ovarian tumor was successfully treated with surgery, improving the patient's symptoms.
1 citations
,
August 2023 in “Case Reports in Women s Health” Leydig cell hyperplasia can cause virilization in postmenopausal women and is treatable with surgery.
12 citations
,
January 2009 in “Gynecological Endocrinology” A postmenopausal woman's hair loss and excess hair growth improved after surgery for ovarian hyperthecosis.
91 citations
,
May 2020 in “Monaldi Archives for Chest Disease” Understanding gender differences in COVID-19 is crucial for effective health strategies.
October 2023 in “Journal of the Endocrine Society” The document concludes that doctors should thoroughly check postmenopausal women with sudden increased male traits for rare conditions like androgen-producing endometrial cancer.
1 citations
,
October 2025 in “Biology of Sex Differences” Gender and social factors, not just biology, affect COVID-19 death rates.
20 citations
,
January 1999 in “Current Pharmaceutical Design” Antiandrogen therapy is effective and well tolerated for treating women's androgenic disorders like hirsutism, acne, and hair loss.
January 2023 in “LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)”
17 citations
,
April 2010 in “Archives of Gynecology and Obstetrics” Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.
December 2022 in “Journal of Medical Case Reports” A 20-year-old woman was found to have a rare ovarian tumor causing symptoms like acne and a low-pitched voice, which disappeared after the tumor was removed.
9 citations
,
January 2017 in “Ginekologia Polska” A higher testosterone to dihydrotestosterone ratio may indicate worse metabolic health in women.
83 citations
,
December 2004 in “American Journal of Obstetrics and Gynecology”
4 citations
,
May 2007 in “Oral and Maxillofacial Surgery Clinics of North America” Understanding gender differences and individual patient characteristics is essential for optimal cosmetic surgery outcomes.
October 2023 in “Journal of the Endocrine Society” A woman's ovarian fibroma caused high testosterone levels, which normalized after surgery.
8 citations
,
September 2020 in “Journal of adolescent health” Gender-affirming care for youth remained essential during the COVID-19 pandemic, with telemedicine playing a key role.
September 2024 in “Brazilian Journal of Case Reports” Clomiphene testing can help find ovarian causes of high testosterone in postmenopausal women.
June 2026 in “Romanian Journal of Medical Practice” Surgery resolved hormone imbalance and symptoms in a rare ovarian tumor case in an elderly woman.
January 2017 in “Research Portal (King's College London)” Mantel's family life affected her view of femininity and worsened her endometriosis.
October 2025 in “Journal of the Endocrine Society” Leydig cell tumors in the ovary can cause high testosterone and male traits in postmenopausal women but are treatable with surgery.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.