32 citations
,
March 1988 in “International Journal of Dermatology” Retinoids can help treat skin disorders by improving the skin's outer layer.
31 citations
,
January 1981 in “Pharmacology & Therapeutics” Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
28 citations
,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
26 citations
,
May 1991 in “Clinical and experimental dermatology” Oral etretinate improved hair length and reduced beading in monilethrix.
24 citations
,
September 2005 in “Journal of Cellular Biochemistry” Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.
22 citations
,
October 2012 in “Journal of Investigative Dermatology” Altered retinoid metabolism in cicatricial alopecia suggests a balanced vitamin A diet may prevent the condition.
21 citations
,
June 1990 in “British Journal of Dermatology” Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
20 citations
,
September 1983 in “Archives of dermatology” The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.
15 citations
,
March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
15 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Retinoids can change the hair growth cycle by extending the growth phase and shortening the rest phase.
7 citations
,
January 2013 in “Journal of Investigative Dermatology” Vitamin A may influence hair loss conditions like alopecia, but more research is needed to understand how.
7 citations
,
August 2009 in “The Journal of Rheumatology Supplement” Retinoids and narrowband UVB phototherapy are effective for treating psoriasis and can reduce treatment time when used together.
2 citations
,
November 2004 in “Blood” RXRa is crucial for Th2 immune cell development and may link nutrition to immune health.
1 citations
,
January 2018 in “Indian Journal of Dermatology/Indian journal of dermatology” Retinoids might cause temporary hyperthyroidism in some patients.
1 citations
,
June 2016 in “Annals of the rheumatic diseases” Retinoids may help treat lupus nephritis and reduce steroid use.
1 citations
,
April 2015 in “The FASEB journal” UVB exposure increases skin proteins for retinoic acid synthesis and shifts their location, possibly affecting skin repair.
May 2025 in “International Journal of Trichology” Oral Acitretin effectively resolved symptoms in a child with Netherton syndrome.
January 2023 in “Journal of cosmetic dermatology” The synthetic retinoid EC23 thickens skin and promotes hair growth more effectively and with a lower dose than natural retinoids.
Retinoids can cause skin issues and hair loss due to their effects on cell membranes.
October 2019 in “CRC Press eBooks” Retinoids can both cause and treat different hair disorders.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
January 2019 in “Social Science Research Network” Hair follicle stem cells prevent melanocyte stem cells from differentiating by controlling retinoic acid levels.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Double-stranded RNA helps regenerate hair follicles by increasing retinoic acid production and signaling.
June 2015 in “OhioLink ETD Center (Ohio Library and Information Network)” UVB exposure affects retinoid metabolism, which is important for skin cancer progression and treatment.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
Retinoids can help treat skin pigmentation disorders by affecting melanin production.
January 2010 in “China Animal Husbandry & Veterinary Medicine” RORs may influence cashmere growth cycles.
The enzyme Dgat1 is essential for healthy hair and skin by controlling retinoid levels.
RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.
January 1990 in “Irish Journal of Medical Science (1971 -)” Retinoids are important for treating skin conditions but should be used with caution due to serious side effects and risks during pregnancy.