research Design and synthesis of novel Azasteroids and Pseudoazulenyl nitrones
The research created new azasteroids and pseudoazulenyl nitrones, which could be useful in medicine.
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240-270 / 1000+ results research Disseminated tinea incognito due to Trichophyton violaceum in a healthy child
A fungal infection was successfully treated with oral and topical antifungals after being misdiagnosed and worsened by corticosteroids.
research Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes
Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
research Leflunomide for the treatment of trichodysplasia spinulosa in a liver transplant recipient
Leflunomide successfully treated a rare skin condition in a liver transplant patient.
research Therapeutic and skincare products used in hirsutism and hypertrichosis
Prescription tablets treat hirsutism, while over-the-counter foams treat hypertrichosis.
research Design, synthesis and anti-tumor evaluation of novel thiohydantoin congeners as androgen receptor antagonists with in vivo study.
A new compound, 3a, effectively fights prostate cancer better than finasteride.
research Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo
Olorofim effectively treats fungal skin infections.
research Eficácia e segurança da triancinolona hexacetonida em comparação com plasma rico em plaquetas e minoxidil no tratamento da alopecia areata
Triamcinolone hexacetonide is effective but has side effects, while PRP and minoxidil are safer alternatives for treating alopecia areata.
research Aromatase inhibition by letrozole attenuates kainic acid-induced seizures but not neurotoxicity in mice
Letrozole reduces seizures but not brain damage in mice.
research Trazodone by epigenetic mechanism can reverse the post finasteride syndrome
Trazodone might help reverse post finasteride syndrome.
research Ultrasound-Assisted Facile Synthesis and Anticancer Evaluation of Novel N-(2-substituted phenyl-4-oxathiazolidine-3-carbonothioyl) benzamide
Researchers made new compounds that could potentially be developed into anticancer drugs.
research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.
research Pustular Eruption in a Patient Treated With Trametinib
Trametinib can cause skin issues, but they can often be managed without stopping the drug.
research Refractory Dermatophytosis in a Spitz Dog Successfully Managed with Posaconazole: A Case Report
Posaconazole successfully treated a resistant skin infection in a Spitz dog when other antifungals failed.
research Multiple Scaly Patches on the Scalp
Itraconazole is effective for treating scalp ringworm, and a Wood's lamp is a useful diagnostic tool.
research Assessment of the Pharmacokinetic -Pharmacodynamic Interaction Between Terazosin and Finasteride
Terazosin and finasteride together cause no major issues.
research Kerion Type of Tinea Capitis Treated with Double Pulse Dose Terbinafine
Double pulse dose terbinafine effectively treats kerion type of tinea capitis.
research An Unusual Case of White Piedra Due to Trichosporon inkin Mimicking Trichobacteriosis
A man's pubic hair infection was treated by shaving and using antifungal medications.
research Concept of tinea capitis
Terbinafine is the most effective treatment for tinea capitis, a scalp infection often confused with other conditions.
research Thiohydrazides in the Synthesis of Functionalized Extranuclear Heterosteroids
New steroid derivatives show promise as anticancer agents, even against resistant cells.
research The Potential Utility of Tirzepatide for the Management of Polycystic Ovary Syndrome
Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.
research The Impact of Lactobacillus-Rich Probiotic Nutrition on the Pharmacological Efficacy of Clotrimazole Delivered via Mucoadhesive Thermosensitive Hydrogels in Human Subjects with Recurrent Candidiasis
Combining probiotics, clotrimazole gel, and laser therapy improves treatment for recurrent yeast infections.
research Alfatradiol/minoxidil/trichofoam
research Ketoconazole Therapy for Women with Acne and/or Hirsutism
Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
research Synthesis, Biological Evaluation and in silico Studies of Novel 5α-aza-Bhomo-3,5-secosteroids as Potential 5-reductase Inhibitors
research Combined drug triads for synergic neuroprotection in retinal degeneration
Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.
research Anticancer agents against malaria: time to revisit?
Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Terbinafine levels in serum, stratum corneum, dermis-epidermis (without stratum corneum), hair, sebum and eccrine sweat.
Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.
research Therapy and Antifungal Susceptibility Profile of Microsporum canis
Terbinafine and itraconazole are more effective against Microsporum canis than fluconazole and griseofulvin.