November 2023 in “Вопросы современной педиатрии” Genetic testing can diagnose hair loss linked to DSG4 gene variants.
18 citations
,
March 2003 in “British journal of dermatology/British journal of dermatology, Supplement” Trichofolliculoma has specific cytokeratin patterns that help in its diagnosis.
5 citations
,
July 1996 in “Journal of Cutaneous Medicine and Surgery” TTD patients don't have a higher skin cancer risk because their main issue is with transcription, not DNA repair.
35 citations
,
December 2008 in “PubMed” Trichilemmoma, BCC, and SCC tumors have different stem cell marker expressions.
Tricholemmoma is linked to Cowden syndrome and can be benign or malignant.
June 2025 in “International Journal of Molecular Sciences” Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
3 citations
,
January 2023 in “Science advances” The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
6 citations
,
March 2017 in “Journal of the European Academy of Dermatology and Venereology” Identical twins with a rare KRT 86 gene mutation both have the hair disorder monilethrix.
990 citations
,
October 1999 in “Development” Activated LEF/TCF complexes are crucial for hair development and cycling.
3 citations
,
March 2017 in “Pediatric Dermatology” FOXN1 duplication can cause excessive hair growth.
November 2017 in “British Journal of Dermatology” Genes controlling hair growth and immune response are disrupted in male pattern baldness.
28 citations
,
July 1980 in “British Journal of Dermatology” The hair disorder was caused by abnormal protein formation, making hair easily damaged.
5 citations
,
September 2012 in “Journal of Investigative Dermatology” Scientists can mimic hair disorders by altering genes in lab-grown human hair follicles, but these follicles lack some features of natural ones.
5 citations
,
October 2012 in “Expert Review of Dermatology” Trichoscopy is a useful tool for diagnosing hair and scalp diseases without needing skin biopsies.
26 citations
,
December 1979 in “Journal of Cutaneous Pathology” Seborrheic keratoses may partly come from hair follicle cells.
June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzymes Tet1, Tet2, and Tet3 are important for the development of hair follicles and determining hair shape by controlling hair keratin genes.
68 citations
,
August 2009 in “American Journal of Medical Genetics Part A” A new classification for trichothiodystrophy helps identify genetic causes and potential treatments.
105 citations
,
February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
9 citations
,
April 2020 in “Journal of dermatology” A person with a specific gene mutation had extra teeth, unique jaw and hair features not seen before in this condition.
44 citations
,
August 2008 in “Archives of Dermatology” Trichoscopy is a non-invasive way to diagnose hair and scalp problems without needing hair samples.
5 citations
,
June 2014 in “Der Hautarzt” Genetic testing can identify causes of rare hair loss disorders in children, but no treatments exist.
June 2015 in “Turkish Journal of Dermatology” Trichoscopy helps diagnose different hair diseases effectively.
72 citations
,
May 1993 in “The Journal of Cell Biology” Trichohyalin in sheep hair follicles may help with structure and calcium binding.
12 citations
,
March 2021 in “Journal of Investigative Dermatology” TRPM5 is crucial for maintaining hair growth.
42 citations
,
October 2012 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing different hair and scalp diseases without surgery.
59 citations
,
September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
1 citations
,
April 2018 in “Turkish Journal of Dermatology” Childhood hypertrichosis is excessive hair growth not linked to hormones, with types based on location and origin.
1 citations
,
January 2025 in “JAAD reviews.” Hypertrichosis involves excessive hair growth and needs careful diagnosis and treatment, considering its psychological effects.
188 citations
,
June 1998 in “Molecular cell” Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.
Trichotillomania treatment is improving with behavior therapy and new drug approaches, but challenges like stigma and underdiagnosis remain.