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The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.

BTNL2 helps protect hair follicles from immune attacks, which could aid in treating alopecia areata.

BMP signaling prevents hair growth by stopping stem cell activation.

Certain immune cells worsen post-surgery gut paralysis by activating a specific immune response.

FTase and GGTase-I are essential for skin keratinocyte health.

Skin tumors with CYLD cutaneous syndrome show more NF-κB activity and less organized collagen.

CRF can cause hair loss, but blocking its receptors might prevent this.

Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.

Deucravacitinib improves symptoms and reduces inflammation in Lichen Planopilaris.

High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.

A new mutation in the KRT86 gene causes a hair disorder with variable expression.

Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.

Overexpressing GLI-1 in mice skin can cause tumors like human basal cell carcinomas.

Trichothiodystrophy is a rare genetic disorder causing hair issues and sometimes linked to DNA repair defects.

Entospletinib effectively prevents eye and skin GVHD in mice.

Androgen receptors help prostate cancer cells grow and resist drugs.

Skin irritants can promote hair growth by affecting specific skin proteins.

GLABRA2 represses root hair formation by inhibiting a specific gene.

MOF controls skin development by regulating genes for mitochondria and cilia.

JAK inhibitors can be safely used in alopecia areata patients with latent hepatitis B or tuberculosis, with proper monitoring.

Keratin 15 affects cell behavior and characteristics in skin cells.

Acid can block TRPV3 from outside the cell but boost its function from inside.

Increasing calcium sensing receptor speeds up skin and hair development in mice.

Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.

JAK inhibitors might help treat alopecia areata.