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Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.

Serotonin helps wounds heal faster.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Melanocyte pathology requires keratinocyte hyperplasia and regulation dysfunction.

Activating TLR3 may help produce retinoic acid, important for tissue regeneration.

CRH causes hair loss by reducing cell survival in hair follicles.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

The research found how GPCR Class A Rhodopsin receptors are related and suggested possible substances they interact with.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.

Two patients had a unique form of trichothiodystrophy with reduced high-sulfur proteins in their hair.

Proteolytic enzymes damaged hair follicle stem cells in transgenic mice.

KB2115 (eprotirome) can safely extend the hair growth phase without damaging cells or changing hair color.

PRC1 is essential for proper skin development and stem cell formation by controlling gene activity.

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

Defective protein folding due to a mutation is key in ANE syndrome.

TCF/Lef1 is essential for skin barrier function by regulating lipid metabolism.

Trichoriboside treatment helps maintain scalp hair by increasing cAMP levels in hair follicles of men with hair loss.

Extracellular ATP is crucial for plant root growth and signaling.

A mutation in the iRhom2 gene causes hairless mice due to abnormal hair follicle development.

Hair follicles have an enzyme that converts arginine to citrulline in proteins.

Different mutations in the 5 alpha-reductase-2 gene were found in affected individuals in the Dominican Republic, suggesting no common ancestry.

TMPRSS2 affects COVID-19 severity and treatment options.

AIMP1 can boost hair growth by increasing stem cell activity.