450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
142 citations
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March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
110 citations
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September 2017 in “Molecules” Forsythiae Fructus has anti-inflammatory, antibacterial, and antiviral properties, with differences between unripe and ripe forms important for clinical use.
90 citations
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December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
73 citations
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December 2015 in “Nature Genetics” Mutations in TBX3 cause horses to have more even hair color instead of Dun camouflage.
51 citations
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March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
50 citations
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April 2021 in “Frontiers in Immunology” New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
49 citations
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November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
46 citations
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April 2021 in “International Journal of Molecular Sciences” Curcumin shows promise in reducing pain and inflammation, but more research is needed.
45 citations
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May 2024 in “International Journal of Molecular Sciences” Alopecia areata is caused by immune attacks on hair follicles, affecting hair growth and quality of life.
40 citations
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November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
37 citations
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January 2019 in “BioMed Research International” Itchy scalp is common, linked to various conditions, and hard to treat effectively.
31 citations
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August 2022 in “Frontiers in Oncology” Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
29 citations
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February 2021 in “Cancers” Ion channels play a key role in ovarian cancer growth and treatment resistance.
28 citations
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June 2021 in “Frontiers in immunology” A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.
27 citations
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January 2016 in “Cellular Physiology and Biochemistry” Bidens pilosa L. extract effectively treats androgen deficiency dry eye in rats.
24 citations
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February 2022 in “Journal of Biological Chemistry” Carvacrol activates the TRPV3 channel, which may help design new skin treatments.
20 citations
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February 2023 in “Biology” Innovative cosmetics could safely change hair color by targeting biological hair pigmentation processes.
19 citations
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February 2016 in “Journal of Biological Chemistry” KCNQ potassium channels help control the sensitivity of touch receptors in the skin.
15 citations
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December 2020 in “The Journal of General Physiology” Acid can block TRPV3 from outside the cell but boost its function from inside.
14 citations
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June 2021 in “Journal of dermatological science” Argan press cake extract might help grow hair and protect hair cells from damage and inflammation.
10 citations
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July 2022 in “Dermatology and Therapy” Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.
9 citations
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
8 citations
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January 2025 in “JADA Foundational Science” Photobiomodulation therapy can reduce pain and inflammation and help heal tissues, but more research is needed to improve its effectiveness and safety.
7 citations
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March 2020 in “Journal of King Saud University. Science/Maǧallaẗ ǧāmiʹaẗ al-malik Saʹūd. al-ʹUlūm” AiQingHua oil improves blood flow and promotes hair growth in mice.
6 citations
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July 2025 in “Frontiers in Microbiology” Imbalanced skin bacteria worsen diabetic foot ulcers, but adjusting them might improve healing.
6 citations
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October 2022 in “Frontiers in Physiology” Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
6 citations
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May 2025 in “Cosmetics” Sunscreen technology is improving with new ingredients and methods to better protect skin from sun damage.
5 citations
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December 2022 in “Toxins” Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
4 citations
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August 2025 in “Journal of Food Science” Tremella fuciformis polysaccharide has many health benefits and potential uses in food, medicine, and cosmetics.