546 citations
,
February 2008 in “PLANT PHYSIOLOGY” OsPHR2 gene causes excessive phosphate in rice shoots, affecting plant growth and root development.
488 citations
,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
365 citations
,
March 2021 in “Frontiers in Bioengineering and Biotechnology” Nanocarriers can improve drug delivery through the skin by overcoming barriers.
344 citations
,
June 2006 in “American Journal Of Pathology” Human hair follicles can provide stem cells for regenerative medicine.
293 citations
,
November 2005 in “Trends in Immunology” Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
213 citations
,
September 2020 in “Journal of Functional Biomaterials” Bio-based electrospun fibers improve wound healing but face production and regulatory challenges.
185 citations
,
January 2010 in “Experimental Dermatology” Probiotics may help reduce stress-related skin issues and improve hair growth.
177 citations
,
March 2018 in “International Journal of Molecular Sciences” mTOR inhibitors may help treat lung fibrosis.
171 citations
,
June 2004 in “Journal of Investigative Dermatology” GLI2 activates GLI1, promoting skin tumor growth and hair development.
158 citations
,
November 1998 in “Cell” β-catenin affects hair growth and can lead to tumors, needing more research for better understanding.
154 citations
,
November 2017 in “Development” Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
142 citations
,
March 2019 in “Molecules/Molecules online/Molecules annual” Cannabinoids may help treat various skin conditions.
124 citations
,
January 1995 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Netherton's syndrome is linked to high IgE levels and unique skin and hair symptoms, and may improve with ammonium lactate lotion and allergy management.
119 citations
,
November 2016 in “American journal of human genetics” Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
107 citations
,
October 2014 in “PeerJ” Hair's molecular structure is mostly consistent, but genetic differences affect lipid types, which could help diagnose diseases.
94 citations
,
April 2018 in “Nature Genetics” New genetic locations explain much of hair color variation in Europeans.
92 citations
,
April 2009 in “Journal of Investigative Dermatology” The Celsr1 gene is crucial for normal hair patterning in mice.
91 citations
,
May 2023 in “Journal of Cutaneous Medicine and Surgery” Alopecia Areata affects 2% globally, with treatments like essential oils, garlic, and JAK inhibitors showing promise, but more research is needed.
90 citations
,
December 2008 in “Journal of Investigative Dermatology” Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.
81 citations
,
March 2006 in “Journal of Investigative Dermatology” Mutations in the DSG4 gene cause specific hair and scalp issues.
80 citations
,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
79 citations
,
November 2016 in “EMBO Reports” Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
77 citations
,
September 2017 in “Journal of Investigative Dermatology” TRPV3 in skin cells causes inflammation and cell death.
76 citations
,
January 2011 in “Indian Journal of Dermatology/Indian journal of dermatology” Dermoscopy is a useful tool for diagnosing and managing alopecia areata.
75 citations
,
August 2018 in “Plant physiology” Hydrogen sulfide disrupts protein function and root hair growth in plants by modifying proteins.
74 citations
,
July 2008 in “Journal of Dermatological Case Reports” Trichoscopy is a quick and easy way to diagnose most genetic hair problems without invasive methods.
68 citations
,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
61 citations
,
September 2024 in “Micromachines” Electrospun nanofiber membranes are promising for non-invasive medical uses like tissue repair and health monitoring.
61 citations
,
April 2023 in “Bioactive Materials” Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.
61 citations
,
October 2011 in “Experimental dermatology” Scalp itching is common and hard to diagnose due to the complex nerve structure of the scalp.