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510-540 / 1000+ resultsresearch Keratins and skin disease
Keratin mutations cause skin diseases and could lead to new treatments.
research 5α-reductase inhibitors impact prognosis of urothelial carcinoma
5α-reductase inhibitors may lower the risk of death from bladder cancer.
research Skin Microbiome, Metabolome and Skin Phenome, from the Perspectives of Skin as an Ecosystem
Your skin is like an ecosystem, with its own community of microbes and substances that interact and affect its health.
research The state‐of‐the‐art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms
New and existing treatments for hair loss show promise, with some being more effective for men and others for women.
research O que sabemos sobre os inibidores da 5 alfa redutase?
Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.
research Emerging concepts: regenerative medicine in dermatology
research Trailing the Path to Preventive Oncology
Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.
research Minimally Invasive Non-Surgical Therapies for Androgenetic Alopecia: A Narrative Review of Clinical Evidence for Regenerative and Locally Acting Antiandrogen Treatments
Platelet-rich plasma, microneedling with minoxidil, and topical finasteride are promising treatments for hair loss.
research Role of Polyphenols in Dermatological Diseases: Exploring Pharmacotherapeutic Mechanisms and Clinical Implications
Polyphenols may help treat skin diseases due to their anti-inflammatory and antioxidant effects.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Keratinization of outer root sheath cells is prevented by contact with inner root sheath of rat hair follicles
research The association of medications and supplements with human male reproductive health: a systematic review
Some medications and supplements can affect male fertility, with some improving and others harming sperm quality.
research Alopecia areata
Alopecia areata is an autoimmune disease with genetic links, treatable with certain medications, and can affect mental health.
research Referee report. For: Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment [version 3; peer review: 2 approved]
Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.
research 5α-Reductases in Human Physiology: An Unfolding Story
Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
research African Hair
research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla
Steroid sulfatase in hair follicles may be a target for treating hair loss.
research Titanium Dioxide Nanoparticles: Effects on Development and Male Reproductive System
Titanium dioxide nanoparticles may harm the male reproductive system.
research Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors
research 5‐Alpha reductase inhibitor related litigation: A legal database review
Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.
research Traditional Chinese Medicine Treatment for Androgenetic Alopecia Based on Animal Experiments: A Systematic Review and Meta-Analysis
Traditional Chinese Medicine may help treat hair loss but needs more research.
research Adverse effects of the 5-alpha-reductase inhibitor finasteride on Daphnia magna: Endocrine system and lipid metabolism disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research The In Vivo and In Vitro Effects of Terminalia bellirica (Gaertn.) Roxb. Fruit Extract on Testosterone-Induced Hair Loss
Terminalia bellirica extract may help promote hair growth and prevent hair loss caused by testosterone.
research Combined Use of Aqueous Extracts and Polysaccharides from Angelica sinensis and Platycladus orientalis Treats Androgenetic Alopecia
research An exploratory analysis of 5‐alpha reductase inhibitors and risk of opioid use disorder among male Medicare beneficiaries receiving prescription opioid medications
Using 5-alpha reductase inhibitors may lower the risk of opioid addiction in men taking opioids.
research Lasers for treatment of androgenetic alopecia: an in-depth analysis
Laser therapy shows promise for hair loss but lacks strong evidence due to limited studies.
research Hair disorders associated with post-COVID-19 infection in females: a cross-sectional study
About 61% of women who had COVID-19 experienced hair loss afterward.
research Evidence for the efficacy and safety of tadalafil and finasteride in combination for the treatment of lower urinary tract symptoms and erectile dysfunction in men with benign prostatic hyperplasia
Taking tadalafil and finasteride together is safe and effective for treating urinary symptoms and erectile dysfunction in men with enlarged prostates.
research Oral Presentations: Abstracts of the Urological Society of Australia and New Zealand Annual Scientific Meeting, 25–28 February 2023, Melbourne, Australia
Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.