106 citations
,
April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
19 citations
,
April 2014 in “Hormones” Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
2 citations
,
March 2018 in “Current Opinion in Urology” 5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
January 2008 in “Springer eBooks” Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
November 2004 in “Medical Journal of Indonesia” Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.
40 citations
,
December 2019 in “Neurobiology of Stress” Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.
32 citations
,
April 2013 in “Anais Brasileiros de Dermatologia” The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
Low-dose oral minoxidil is safe and effective for treating hair loss, with most side effects being mild and reversible.
499 citations
,
September 2011 in “Cell” Fat-related cells are important for initiating hair growth.
91 citations
,
May 2003 in “American Journal of Pathology” Prolactin affects hair growth cycles and can cause early hair follicle regression.
82 citations
,
March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
79 citations
,
January 2018 in “Wiley Interdisciplinary Reviews-Developmental Biology” Understanding how baby skin heals without scars could help develop treatments for adults to heal wounds without leaving scars.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
66 citations
,
January 2001 in “Vitamins and hormones” Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.
64 citations
,
March 2005 in “Journal of Investigative Dermatology” Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.
57 citations
,
February 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
49 citations
,
November 2014 in “Journal of Medicinal Food” Red Ginseng Extract may help human hair grow by activating growth pathways and blocking negative effects of certain hormones.
28 citations
,
January 2016 in “Vitamins and hormones” Thymosin β4 helps improve skin healing and reduce scarring.
19 citations
,
July 2018 in “Mechanisms of Ageing and Development” Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.
12 citations
,
August 2018 in “Journal of Dermatological Science” Scientists made stem cells that can grow hair by adding three specific factors to them.
12 citations
,
September 2017 in “Molecular and Cellular Endocrinology” Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.
12 citations
,
July 2014 in “Journal of Investigative Dermatology” Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
10 citations
,
May 2019 in “Seminars in Cell & Developmental Biology” Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.
10 citations
,
September 2018 in “Regenerative Medicine” New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.
7 citations
,
March 2017 in “Medical Hypotheses” Aquaporins could be new drug targets for treating polycystic ovary syndrome.
5 citations
,
January 2023 in “Nature cell biology” A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
January 2023 in “Biomedicine & Pharmacotherapy” Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.