98 citations
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December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
68 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” HOXC13 is essential for hair and nail development by regulating Foxn1.
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November 1991 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Keratins 8 and 14 can help identify and diagnose benign skin tumors.
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June 2017 in “Advances in Therapy” New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.
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April 1993 in “PubMed” Human hair cells can change based on their environment, especially interactions with certain skin cells.
1 citations
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January 2015 in “Indian Journal of Veterinary Pathology” Two dogs had different types of hair follicle tumors.
January 2025 in “Kuwait Journal of Science” KRT71 gene variants may influence camel hair shape but don't fully explain it.
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August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Androgens promote beard growth but cause hair loss in androgenetic alopecia, with TGF-β1 as a potential treatment target.
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November 2012 in “Journal of Investigative Dermatology” Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
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October 1999 in “Journal of Clinical Investigation” Activating the Sonic hedgehog gene in mice can start the hair growth phase.
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January 2002 in “Nucleic Acids Research” BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
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July 2019 in “Cosmetics” Beautiful hair is flexible and elastic due to its unique double-layered structure and can be enhanced with succinic acid treatment.
January 2016 in “Case reports in clinical medicine” A 6-year-old girl was diagnosed with a rare hair disorder called monilethrix.
23 citations
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April 2016 in “Journal of Visualized Experiments” The method successfully isolates hair follicle stem cells from mice for research.
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February 2006 in “Genomics” A new genetic mutation in mice causes permanent hair loss and skin wrinkling.
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January 1988 Hair follicles have unique proteins that vary by species and are influenced by nutrition.
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July 2019 in “PLoS ONE” Deleting podoplanin in mice promotes hair growth by enhancing cell migration.
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September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
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January 1988 Only two of the four keratin genes are expressed in wool fibers.
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March 2017 in “Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego” Domestic cat hair varies in thickness and length, with guard hairs being longest and thickest, and all hair types mainly contain keratin.
May 2026 in “Frontiers in Endocrinology” Exposure to particulate matter worsens postpartum hair loss by affecting inflammation and cell death pathways.
January 2022 in “Nasza Dermatologia Online” Dermoscopy helps doctors recognize a type of benign skin tumor called pilomatricoma.
December 2020 in “Daehanhanuihakoeji” Rumex japonicas Houttuyn ethanol extract helps increase hair growth and protect against hair damage.
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August 2004 in “Physiological Genomics” Dermal papilla cells help skin stem cells grow into hair.
December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.
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January 2006 in “Molecular & Cellular Proteomics” Human hair contains many proteins, with some being highly abundant and modified.
100 citations
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December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
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December 2000 in “The journal of cell biology/The Journal of cell biology” Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
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March 2017 in “Experimental Dermatology” Curly hair is influenced by specific genetic variations.
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February 2006 in “Journal of Investigative Dermatology” Cylindromas likely originate from hair follicle stem cells, not sweat glands.